Abstract:During neurosurgery, an optical probe has been used to guide the micro-electrode, which is punctured into the globus pallidus (GP) to create a lesion that can relieve the cardinal symptoms. Accurate target localization is the key factor to a®ect the treatment. However, considering the scattering nature of the tissue, the \look ahead distance (LAD)" of optical probe makes the boundary between the di®erent tissues blurred and di±cult to be distinguished, which is de¯ned as artifact. Thus, it is highly desirable … Show more
“…It can realize non-destructive analysis and in vivo real-time monitoring, which can be used for non-destructive or minimally invasive detection of bone tumors. In previous studies, Li et al carried out a real-time minimally invasive study of the vertebral tissue scattering characteristics based on near-infrared technology 26 . In this paper, based on the pre-developed near-infrared detection equipment, the curative effect evaluation factors of bone tissue before and after microwave ablation were studied, and the changes of different factors were compared, which laid the foundation for quantitative evaluation of tissue thermal damage in microwave ablation.…”
Background:Microwave hyperthermic tumor ablation has played an important role in the treatment of bone tumors because of its obvious curative effect, less side effects and fewer complications. The real-time evaluation of the curative effect in microwave ablation of bone tumors is a research tissue. In this paper, it proposes to study the ablation effect of bone tissue by near-infrared spectroscopy and optical parameters. First, bone tissue heating experiment was used to verify the difference in bone tissue near-infrared spectrum before and after heating. Results: In bone tissue microwave ablation experiment, it studied the changes of tissue near-infrared spectrum and optical parameters (reduced scattering coefficient, slope factor, area factor) during specific microwave ablation conditions. It was found that some factors (area(500-550), slope(524-532) and slope(565-570)) changed significantly, correlated with microwave ablation time, which could be used as evaluation factors of microwave ablation. Conclusions: The results lay a foundation for the development of a new method for real-time evaluation of ablation efficacy.
“…It can realize non-destructive analysis and in vivo real-time monitoring, which can be used for non-destructive or minimally invasive detection of bone tumors. In previous studies, Li et al carried out a real-time minimally invasive study of the vertebral tissue scattering characteristics based on near-infrared technology 26 . In this paper, based on the pre-developed near-infrared detection equipment, the curative effect evaluation factors of bone tissue before and after microwave ablation were studied, and the changes of different factors were compared, which laid the foundation for quantitative evaluation of tissue thermal damage in microwave ablation.…”
Background:Microwave hyperthermic tumor ablation has played an important role in the treatment of bone tumors because of its obvious curative effect, less side effects and fewer complications. The real-time evaluation of the curative effect in microwave ablation of bone tumors is a research tissue. In this paper, it proposes to study the ablation effect of bone tissue by near-infrared spectroscopy and optical parameters. First, bone tissue heating experiment was used to verify the difference in bone tissue near-infrared spectrum before and after heating. Results: In bone tissue microwave ablation experiment, it studied the changes of tissue near-infrared spectrum and optical parameters (reduced scattering coefficient, slope factor, area factor) during specific microwave ablation conditions. It was found that some factors (area(500-550), slope(524-532) and slope(565-570)) changed significantly, correlated with microwave ablation time, which could be used as evaluation factors of microwave ablation. Conclusions: The results lay a foundation for the development of a new method for real-time evaluation of ablation efficacy.
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