A real-life study of the medium to long-term effectiveness of a hypercaloric, hyperproteic enteral nutrition formula specifically for patients with diabetes on biochemical parameters of metabolic control and nutritional status

Pomar, María Dolores Ballesteros; Sánchez, Beatriz Lardiés; Argente, María; Carrasco, Araceli Ramos; Gutiérrez, Lorena Suárez; Arrieta, Alfredo Yoldi; Carreras, Patricia Sorribes; Medina, Sonsoles Gutiérrez; Soria, Juan Bautista Molina; Miranda, María Berrio; Martínez, M. Socorro Leyva; Suau, Óscar Torregrosa; Usieto, M. Teresa Olivan; González, Francisco Villazón; Osinaga, J. Abilés; Echevarría, Esteban Martín; García‐Malpartida, Katherine

doi:10.1016/j.endien.2022.04.001

Cited by 1 publication

(2 citation statements)

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“…Albumin is the most abundant circulating protein in healthy subjects, representing nearly 50% of the total protein content in the human body. An intervention study of diabetes patients showed that patients with well nutritional status during a 6-month nutritional treatment showed an increment in albumin level compared with untreated patients [31]. And lower glycemic variability and HbA1c levels were also observed in patients after nutritional treatment [31].…”

Section: A1 B1 A2 B2mentioning

confidence: 99%

“…An intervention study of diabetes patients showed that patients with well nutritional status during a 6-month nutritional treatment showed an increment in albumin level compared with untreated patients [31]. And lower glycemic variability and HbA1c levels were also observed in patients after nutritional treatment [31]. A previous study of DKD patients found that nephrogenic loss of albumin might induce a compensatory increase in hepatic albumin synthesis that increases the turnover for albumin [32] which suggested that a higher level of serum albumin may indicate more severe kidney disease and poorer glycemic control.…”

Section: A1 B1 A2 B2mentioning

confidence: 99%

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Low Blood Glucose Index Associated with Cardiovascular Events in Diabetic Hemodialysis Patients

He,

Xuan,

Zhu

et al. 2023

Blood Purif

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Introduction: Blood glucose monitoring was vitally important in diabetic kidney disease (DKD) patients for preventing complications and improving survival rates. The associations between glycemic variability and blood biochemical indicators were underestimated in patients with DKD undergoing hemodialysis. Therefore, we primarily aimed to investigate the glycemic variability and 1-year risk of cardiovascular disease events in diabetic hemodialysis patients. And we secondarily aimed to explore the association between glycemic variability and blood biochemical indicators. Methods: In total, 27 patients were included in the final analysis. Continuous glucose monitoring (CGM) was used to evaluate glucose variability for 14 days. Patients were divided into two groups by the cutoff level of time in range (TIR; >70% or ≤70%). The three-point major adverse cardiovascular event (3P MACE) was recorded within 1 year. Results: After 1 year of follow-up, 4 patients in the high-TIR group and 3 patients in the low-TIR group had 3p MACE. Higher low blood glucose index (LBGI) level in diabetic hemodialysis patients increased the risk of 3p MACE outcomes (HR = 2.37, p = 0.018). And the level of albumin was positively associated with LBGI (β = 0.51, p = 0.036). The plasma levels of albumin, glycosylated hemoglobin, and hemoglobin were positively associated with other CGM parameters. Conclusion: LBGI during 14 days was positively associated with the risk of cardiovascular events in diabetic hemodialysis patients.

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Section: A1 B1 A2 B2mentioning

confidence: 99%