A re‐analysis of about 60,000 sparse data meta‐analyses suggests that using an adequate method for pooling matters
Maxi Schulz,
Malte Kramer,
Oliver Kuss
et al.
Abstract:In sparse data meta‐analyses (with few trials or zero events), conventional methods may distort results. Although better‐performing one‐stage methods have become available in recent years, their implementation remains limited in practice. This study examines the impact of using conventional methods compared to one‐stage models by re‐analysing meta‐analyses from the Cochrane Database of Systematic Reviews in scenarios with zero event trials and few trials. For each scenario, we computed one‐stage methods (Gener… Show more
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