A rare widespread tuberculous spondylitis extended from the T5-T10 levels – a case report

Evayanti, Luh Gde; Kalanjati, Viskasari Pintoko; Machin, Abduloh

doi:10.1088/1757-899x/434/1/012323

Cited by 3 publications

(2 citation statements)

References 5 publications

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“…TNF-α is known as cachectin that works in the hypothalamus by suppressing the appetite center causing anorexia. Increased TNF-α can be detected in the MN-cell supernatant of peripheral blood of pulmonary tuberculosis patients 16 . Immune response pulmonary tuberculosis patients is active before and after treatment, and rreporting an increase of TNF-α levels during treatment although not significant.…”

Section: Discussionmentioning

confidence: 99%

Changes in ARB Sputum Positivity, BMI and TNF-? Levels of Pulmonary TB Patients with ARB Positive During One-month Intensive Treatment

Samsuri¹

2020

IJFMT

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Backgoround: TNF-α plays a role in the occurrence of anorexia and weight loss in pulmonary tubercolusis (TB) patients. Evaluation of treatment response can be done with clinical, microbiological and radiological evaluation. In patients without cough, Body Mass Index (BMI) and TNF-α levels can be used to evaluate clinical treatment response. Objectives:The aim of the study is to measure the Acid Resistant Bacteria (ARB) sputum positivity decrease, TNF-α levels and increased BMI after 2 weeks and 4 weeks intensive treatment of pulmonary TB patients with new case of ARB positive. Methods:The sample size was 14 people with ARB positive pulmonary TB cases, consisting of 9 men and 5 women. It was done sputup smear, BMI and TNF-α examination before treatment, at week 2 and week 4 of intensive phase treatment Result: At the end of the second week, TNF-α levels decreased significantly compared to baseline TNF-α levels with p = 0.015. There was a non significant increase of BMI at the end of the second and fourth week with p = 0.309 and p = 0.270 respectively. The decrease in ARB sputum smear positivity at the end of the second week compared to the fourth week was not statistically significant with p = 0.157. There was a strong correlation between TNF-α and IMT levels before treatment with negative correlation, r = -0.702 and p = 0.005. Conclusion:Levels of TNF-α at the end of the second week decreased significantly compared to baseline TNF-α levels. There was a strong correlation between TNF-α levels and BMI prior to treatment.

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Section: Discussionmentioning

confidence: 99%

Changes in ARB Sputum Positivity, BMI and TNF-? Levels of Pulmonary TB Patients with ARB Positive During One-month Intensive Treatment

Samsuri¹

2020

IJFMT

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“…Neurological deficits in tuberculous spondylitis result from the formation of cold abscesses, granulation tissues, necrotic tissue and sequestra of bone or intervertebral disc tissue and occasionally vascular thrombosis of the spinal artery 5 . Tuberculous spondylitis is a chronic disease and slow to progress with longlasting symptoms 1 .…”

Section: Introductionmentioning

confidence: 99%

Conservative & Operative Management of Tuberculous Spondylitis in Children

2020

IJFMT

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Background: Tuberculosis is a deadly disease worldwide. Tuberculosis usually occurs in the lung, but there are other tuberculosis most commonly afflicted by the patient and involves the spine and is called tuberculosis of bones and joints. Management of tuberculous spondylitis is conservative and operative.Aim: This study aimed to compare the results of conservative and operative therapy in the management of tuberculous spondylitis in children. Methods:The sample used was teaching with tuberculous spondylitis in Dr. Soetomo General Hospital who underwent operative and conservative therapy that became group 1 and group 2. Inclusion criteria included patients aged <18 years old, suffering from tuberculous spondylitis by conservative or operative therapy in Dr. Soetomo Hospital. Results:In patients receiving conservative therapy, the Visual analog scale (VAS) decreased significantly (p = 0.001), while frankle improved but not significantly (p = 0.157). Cobb's angle of patients receiving conservative therapy increased significantly (p = 0.007). Patients who received operative therapy showed significant improvement of VAS and Frankle (p = 0.001 and p = 0.011). The patient's Cobb's angle after surgery decreased but it was not significant (p = 0.575). Conclusion:The role of surgical action has an important role in the treatment of tuberculous spondylitis and gives better results than conservatives in patients with pain, neurological deficits and Cobb's angle progression.

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Lumbosacral tuberculosis, a rare manifestation of Pott's disease – How identified human skeletons from the pre-antibiotic era can be used as reference cases to establish a palaeopathological diagnosis of tuberculosis

et al. 2023

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A rare widespread tuberculous spondylitis extended from the T5-T10 levels – a case report

Cited by 3 publications

References 5 publications

Changes in ARB Sputum Positivity, BMI and TNF-? Levels of Pulmonary TB Patients with ARB Positive During One-month Intensive Treatment

Changes in ARB Sputum Positivity, BMI and TNF-? Levels of Pulmonary TB Patients with ARB Positive During One-month Intensive Treatment

Conservative & Operative Management of Tuberculous Spondylitis in Children

Lumbosacral tuberculosis, a rare manifestation of Pott's disease – How identified human skeletons from the pre-antibiotic era can be used as reference cases to establish a palaeopathological diagnosis of tuberculosis

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