A Rare Presentation of Paraneoplastic Striatal Encephalitis Associated with Nonsmall Cell Lung Cancer

Reversible Acute Parkinsonism and Unusual Neuroimaging Findings in Systemic Lupus Erythematosus

“…5 Paraneoplastic striatal encephalitis is associated with the presence of CV2/CRMP5, Ri, Ma2, and/or Hu antibodies, and the disabling disease course is a red flag. 6 Encephalitis without underlying neoplasm, such as related with leucine-rich glioma-inactivated 1, dipeptidyl-peptidase-like protein 6, and glutamic acid decarboxylase antibodies, could also manifest with parkinsonism. In children and young adults, especially if associated with behavior change, the differential diagnosis must include tests for N-methyl-D-aspartate receptor and dopamine receptor 2 antibodies.…”

“…For the past decades, several onconeural antibodies have been described in autoimmune encephalitis, and parkinsonism may be observed in some forms . Paraneoplastic striatal encephalitis is associated with the presence of CV2/CRMP5, Ri, Ma2, and/or Hu antibodies, and the disabling disease course is a red flag . Encephalitis without underlying neoplasm, such as related with leucine‐rich glioma‐inactivated 1, dipeptidyl‐peptidase‐like protein 6, and glutamic acid decarboxylase antibodies, could also manifest with parkinsonism.…”