A Rare Intrascrotal Metastases From Renal Cell Carcinoma: A Case Report

Abstract

Metastatic renal cell carcinoma is potentially a lethal disease with in some cases aggressive behavior. The given fact that the patterns of metastases from RCC are not clearly identified, which may involve some rare metastatic locations. We present a case of 58 years old male presented with painless left scrotal mass, which was discovered to be an intrascrotal metastases appeared 3 years after nephrectomy for ipsilateral renal cell carcinoma. We believe that the rarity of the metastatic site and the intriguing possible mechanism of spread make an interesting case for clinicians and could add more follow-up measures for patients treated from renal cell carcinoma.

Synchronous mixed germ cell tumor of testis and renal cell carcinoma: A rare presentation

“…Renal cell carcinoma, the most common type of renal malignant disease, accounts for 2%–3% of all adult malignant neoplasms [4]. The majority of renal malignant neoplasms are now diagnosed incidentally by cross-sectional imaging or ultrasound evaluation of other nonspecific complaints [5]. Historically, renal cell carcinoma was diagnosed only at an advanced stage because of its location within the retroperitoneum.…”

Axillary skin metastasis of renal cell carcinoma—Case report

“…The most common pathway for distant dissemination of the tumor cells is through the lymphatic vessels to the proximal lymph nodes (paracaval/paraortic/interaortocaval lymph nodes) and then ascending through the thoracic duct to the head and neck region [4], [5]. One alternative way of dissemination is the hematogenous path through the paraspinal venous plexus (Batson’s plexus) which drains the blood from the multiple arteriovenous fistulae formed during the process of neoplastic angiogenesis [2], [4], [5], [6]. These two pathways of dissemination could account for the unusual metastatic site occurrence especially in the head, neck and trunk [2], [6].…”

“…One alternative way of dissemination is the hematogenous path through the paraspinal venous plexus (Batson’s plexus) which drains the blood from the multiple arteriovenous fistulae formed during the process of neoplastic angiogenesis [2], [4], [5], [6]. These two pathways of dissemination could account for the unusual metastatic site occurrence especially in the head, neck and trunk [2], [6].…”