A Rare Cause of Weight Loss and Night Sweats

Radersma, Marijn; Mulder, Chris J.; Tushuizen, Maarten E.

doi:10.1053/j.gastro.2014.05.032

Cited by 2 publications

(2 citation statements)

References 2 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Endoscopy can identify abnormal mucosa in most patients; however, it is nonspecific. To date, only a few case reports[ 7 8 9 10 11 12 13 14 15 16 ] have detailed the endoscopic features of EATLs. The endoscopic appearances of EATL are still largely unknown.…”

Section: Discussionmentioning

confidence: 99%

“…[ 1 2 6 ] To date, only a few case reports have detailed the endoscopic morphologic features of EATLs. [ 7 8 9 10 11 12 13 14 15 16 ] In addition, due to a lack of specific endoscopic features, it is difficult to distinguish EATLs and other GI diseases, such as inflammatory bowel disease (IBD) and GI solid tumors, at the time of presentation. To advance knowledge of this disease, we retrospectively reviewed the cases of EATLs diagnosed within a 13-year period in a single tertiary center and summarized the clinical characteristics and endoscopic features of the EATLs.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Endoscopic features and clinical outcomes of enteropathy-associated T-cell lymphoma: A tertiary center retrospective study

Chen

Zhang

Shi

2022

Saudi J Gastroenterol

View full text Add to dashboard Cite

Background: Enteropathy-associated T-cell lymphoma (EATL) is a rare but aggressive primary gastrointestinal lymphoma. The initial complaints of EATL patients are usually gastrointestinal symptoms, but the diagnosis is very difficult. Endoscopy can identify abnormal mucosa in most patients. However, the endoscopic appearance of EATL is still largely unknown. Methods: In this retrospective study, we investigated the endoscopic and clinical features of patients with EATLs at a tertiary center, from January 2008 to October 2020. Results: From a total of 248 patients with primary intestinal lymphoma, only 11 patients were finally diagnosed with EATLs, all of which were EATL type II. Men were affected twice as commonly as women. The median patient age was 47 years. The most common initial symptom was diarrhea (63.6%). Five patients (45.4%) were at late stage (IV) at diagnosis. The endoscopic appearances were classified into four distinct types: ulcerative type (54.5%), epithelial mass type (18.2%), diffuse infiltration type (9.1%), and nodular type (18.2%). The small bowel was the most common site of involvement (72.7%). The initial endoscopic impression of lymphoma was made in only 3 patients (27.3%). Only 4 patients (36.4%) were histologically confirmed as having EATLs based on the initial biopsy specimen. Five patients (45.5%) received emergency surgery. The median overall survival (OS) was 8 months. The use of chemotherapy and the absence of emergency surgery were associated with a significantly better median OS ( P < 0.05). Conclusions: EATL may show various endoscopic appearances, and its prognosis is poor. Endoscopists should obtain more knowledge of EATL in order to make an early diagnosis.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Endoscopic features and clinical outcomes of enteropathy-associated T-cell lymphoma: A tertiary center retrospective study

Chen

Zhang

Shi

2022

Saudi J Gastroenterol

View full text Add to dashboard Cite

show abstract

Rare gastrointestinal lymphomas: The endoscopic investigation

Vetro

Bonanno

Giulietti

et al. 2015

WJGE

View full text Add to dashboard Cite

Gastrointestinal lymphomas represent up to 10% of gastrointestinal malignancies and about one third of non-Hodgkin lymphomas. The most prominent histologies are mucosa-associated lymphoid tissue lymphoma and diffuse large B-cell lymphoma. However, the gastrointestinal tract can be the site of rarer lymphoma subtypes as a primary or secondary localization. Due to their rarity and the multifaceted histology, an endoscopic classification has not been validated yet. This review aims to analyze the endoscopic presentation of rare gastrointestinal lymphomas from disease diagnosis to follow-up, according to the involved site and lymphoma subtype. Existing, new and emerging endoscopic technologies have been examined. In particular, we investigated the diagnostic, prognostic and follow-up endoscopic features of T-cell and natural killer lymphomas, lymphomatous polyposis and mantle cell lymphoma, follicular lymphoma, plasma cell related disease, gastrointestinal lymphomas in immunodeficiency and Hodgkin's lymphoma of the gastrointestinal tract. Contrarily to more frequent gastrointestinal lymphomas, data about rare lymphomas are mostly extracted from case series and case reports. Due to the data paucity, a synergism between gastroenterologists and hematologists is required in order to better manage the disease. Indeed, clinical and prognostic features are different from nodal and extranodal or the bone marrow (in case of plasma cell disease) counterpart. Therefore, the approach should be based on the knowledge of the peculiar behavior and natural history of disease.

show abstract

A Rare Cause of Weight Loss and Night Sweats

Cited by 2 publications

References 2 publications

Endoscopic features and clinical outcomes of enteropathy-associated T-cell lymphoma: A tertiary center retrospective study

Endoscopic features and clinical outcomes of enteropathy-associated T-cell lymphoma: A tertiary center retrospective study

Rare gastrointestinal lymphomas: The endoscopic investigation

Contact Info

Product

Resources

About