A rare cause of non discal sciatica: Schwannoma of the sciatic nerve

Omezzine, S. Jerbi; Zaara, B.; Ali, Manazir; Abid, Faouzi; Sassi, Narjes; Hamza, H.A.

doi:10.1016/j.otsr.2009.05.007

Cited by 36 publications

(39 citation statements)

References 13 publications

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“…The most common clinical presentation of sciatic nerve schwannoma consists of a painful palpable mass. 9,11,13 Schwannomas most commonly occur in adults between 20 and 50 years of age. Schwannomas are usually homogeneous on both T1-and T2-weighted images but a neurofibroma is usually heterogeneous.…”

Section: Discussionmentioning

confidence: 99%

Neglected Giant Schwannoma of the Sciatic Nerve. Case Report and Literature Review

ElEmam

Hasan

Elsebaey

2018

Egyptian Spine Journal

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Background Data: Schwannomas originating from the sciatic nerve are extremely rare and usually present as a pathological mass on palpable examination or pain located in the thigh. Motor and sensory deficits are observed more often with big size lesions. Purpose: To describe a rare case of giant schwannoma of the sciatic nerve with 2 years delay in management. Study Design: Case report and review of the literature. Patients and Methods: A 19-years-old female patient was referred to Suez Canal University Hospital after 6 years of pain and 2 years of improper management. She presented with increasing swelling in the posterior aspect of her right thigh associated with paresthesia and weakness. After neurological examination an MRI of the right thigh was done and revealed huge mass attached to the right sciatic nerve. Results: Surgical excision was undertaken, carefully dissecting the lesion from the sciatic nerve. Histopathological examination revealed a sciatic nerve schwannoma. The patient had marked postoperative recovery with marked pain reduction and improved neurological deficits. Conclusion: Schwannomas of the sciatic nerve are eccentrically located on the nerve. they should be systematically suspected if thigh mass or persistent sciatica is reported. Surgical excision has good prognosis. (2018ESJ157)

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Section: Discussionmentioning

confidence: 99%

Neglected Giant Schwannoma of the Sciatic Nerve. Case Report and Literature Review

ElEmam

Hasan

Elsebaey

2018

Egyptian Spine Journal

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“…It is a heterogenous group of tumour arising from the Schwann cells or the perineural cells (Omezzine et al, 2009). It accounts for 3%~10% of all soft tissue sarcoma (Katz et al, 2009).…”

Section: Discussionmentioning

confidence: 99%

“…It accounts for 3%~10% of all soft tissue sarcoma (Katz et al, 2009). Almost half of the MPNST are associated with Type 1 Neurofibromatosis or von-recklinghausen's disease, an autosomal dominant disease which is associated with inactivation of NF1 gene (Omezzine et al, 2009;Katz et al, 2009;Dimou et al, 2009). It can also be associated with post-radiation.…”

Section: Discussionmentioning

confidence: 99%

A Case Report of Malignant Peripheral Nerve Sheath Tumour (Mpnst) Which Present as An Acute Traumatic Sciatic Neuropathy

Wong¹,

Chan²

2014

ijccr

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Malignant peripheral nerve sheath tumour (MPNST) is a very rare sarcoma and it accounts for around 5% of all sarcoma.We are reporting an interesting case of sporadic MPNST at the proximal sciatic nerve which concealed as a traumatic cause of sciatic neuropathy and foot drop. A 59 year old Caucasian lady presented with a constant paraesthesia and pain at her left hip after she had a fall. On examination, there was marked neurological impairment along the L4, L5 and S1 distribution. A MRI of the pelvis was performed. It revealed a large soft tissue mass at the centre of the left buttock arising from the proximal sciatica nerve. The biopsy result revealed the diagnosis of malignant peripheral nerve sheath tumour (MPNST). She underwent a complete resection of tumour with clear margins of the tumour. A vigilance MRI examination was performed 5 months post-operatively and no evidence suggesting of local recurrences. However, 10 months after the operation a surveillance CT scan was performed and it revealed presence of pulmonary metastases. MPNST is a heterogenous group of tumour arising from the Schwann cells or the perineural cells. The presentation is usually subtle and invariably leads to a late diagnosis of the disease. The prognosis is often poor. The mainstay of treatment is surgical resection. However, despite complete resection, the tumour can recur and metastasis. A continuous paraesthesia and pain along nerve root must raise the suspicion among clinicians about the possibility of extraspinal causes of sciatica.

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“…Operasyon sırasında tümör kapsülü üzerinden uzunlamasına insizyon yapılarak tümör kitlesi sinir fibrilleri arasından basit enükleasyon ve dikkatli diseksiyon ile eksize edilir (7)(8)(9). Bu karakteristik olarak Schwannomu nörofibromdan ayırır, nörofibromda sinir fibrilleri tümör ile karışmıştır.…”

Section: Olguunclassified

Schwannoma Of The Scıatıc Nerve: Two cases

Özdemir¹,

Küçük²,

Sabah³

et al. 2012

Tepecik Dergisi

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ÖZET39 ve 44 yaşındaki iki erkek hastada sırasıyla 15 ve 3cm.lik sağ uyluk kitlesi, ek olarak ikinci hastada sağ tibyal posterior sinirden köken alan 8mm.lik bir tümör saptandı. Büyütme eşliğinde sinir dalları korunarak çıkarılan kitlelerin patolojik tanısı Schwannoma geldi. Sırasıyla 38 ve 27 ay sonraki kontrollerde yineleme görülmedi. Nadir oluşları ve sinir koruyucu cerrahi ile tedavi edilebileceği vurgulandı.Anahtar sözcükler: Biopsi, Mikrodiseksiyon, Nörilemmoma, Periferik sinirler. SUMMARY15 and 3cm mass in right thighs of two male patient who are 39 and 44 years old were found. Second patient had another mass(8mm in diameter) originating from right nervus tibialis posterior. The pathologic diagnosis of these masses resected by preserving nerve under magnification were Scwannoma. There was no recurrence after 38 and 27 months respectively. Their rarity and resectability without sacrifiying the nerve were the characteristics of the cases.

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A rare cause of non discal sciatica: Schwannoma of the sciatic nerve

Cited by 36 publications

References 13 publications

Neglected Giant Schwannoma of the Sciatic Nerve. Case Report and Literature Review

Neglected Giant Schwannoma of the Sciatic Nerve. Case Report and Literature Review

A Case Report of Malignant Peripheral Nerve Sheath Tumour (Mpnst) Which Present as An Acute Traumatic Sciatic Neuropathy

Schwannoma Of The Scıatıc Nerve: Two cases

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