A rare cause of intestinal bleeding: duodenal metastasis from endometrial cancer

Leitão, Cátia; Caldeira, Ana Teresa; Banhudo, António

doi:10.17235/reed.2017.4822/2017

Cited by 4 publications

(3 citation statements)

References 3 publications

(3 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Small intestine metastases from EC may clinically present with abdominal cramps, melena, secondary anemia, and epigastric pain [ 3 , 6 , 7 ]. In this case, the patient presented with an enterocutaneous fistula and surrounding skin inflammation.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Small intestine metastasis from endometrial carcinoma initially presented as enterocutaneous fistula: a case report and literature review

Nikolovski,

Limani,

Ristova Tancheva

et al. 2024

Journal of Surgical Case Reports

View full text Add to dashboard Cite

Although endometrial cancer is the fourth most common malignancy among women, it rarely metastasizes to the small intestine. Cases of endometrial recurrence to the intestine clinically present with secondary anemia, melena, abdominal cramps, and epigastric pain. Only a dozen cases are reported in the literature, but none presented with an enterocutaneous fistula. In this report, we present a case of an 88-year-old female patient previously treated for endometrial adenocarcinoma with surgery and adjuvant radiotherapy. Fourteen months after the surgery, the patient presented with an enterocutaneous fistula on the anterior abdominal wall, which was confirmed to be a metastasis from the primary tumor. To our knowledge, this is the first case of endometrial cancer metastasizing to the small intestine with involvement of the anterior abdominal wall and the occurrence of an enterocutaneous fistula, which was treated with radical surgery.

show abstract

Section: Discussionmentioning

confidence: 99%

“…Additional immunohistochemistry staining differentiates intestinal metastases from other primary adenocarcinomas, especially colorectal cancer. EC shows positivity to CK 7, PAX8, Estrogen Receptor, and Progesterone Receptor [ 7 , 9 ].…”

Section: Discussionmentioning

confidence: 99%

Small intestine metastasis from endometrial carcinoma initially presented as enterocutaneous fistula: a case report and literature review

Nikolovski,

Limani,

Ristova Tancheva

et al. 2024

Journal of Surgical Case Reports

View full text Add to dashboard Cite

show abstract

“…Duodenal malignant was extremely rare and duodenal adenocarcinoma was a primary tumor for malignant disease. Duodenal metastasis could result from other organs, including the breast, lung, kidney, prostate, liver, colon, and uterus [ 18 – 20 ]. The thickness of the duodenal wall in the current study was quite large and biopsies from conventional endoscopy were negative.…”

Section: Discussionmentioning

confidence: 99%

EUS-guided fine needle aspiration provides an open view for duodenal obstruction caused by urothelial carcinoma: a case report

Chen

et al. 2022

BMC Gastroenterol

View full text Add to dashboard Cite

Background Endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) is a good alternative and diagnostic tool for gastrointestinal wall thickening with prior negative endoscopic biopsies. Case presentation Here we reported a case of a 60-years-old woman admitted with atrophic right kidney and hydronephrosis and intermittent postprandial bloating. Esophagogastroduodenoscopy and small bowel endoscopy revealed wall thickening and stenosis at the junction of the descending and inferior duodenum. Biopsies from endoscopy showed no specific findings. EUS-FNA of the thickened duodenal wall was performed and histopathological examinations revealed poorly differentiated carcinoma. Immunohistochemically staining was positive for pan-cytokeratin, CK7, CK20, and weakly positive for GATA-3 and P63. These results were highly suggestive of metastatic urothelial cancer. Conclusions EUS-FNA played an important role in the diagnosis of unexplained gastrointestinal wall thickening and rare metastases to the gastrointestinal wall.

show abstract

Metastatic clear cell endometrial carcinoma: an unusual cause of a common clinical presentation

2020

View full text Add to dashboard Cite

A 60-year-old woman presented with melena for 2 weeks. She had undergone hysterectomy and bilateral salpingo-oophorectomy to treat clear cell endometrial carcinoma 10 months before the presentation. She was anaemic and tachycardic; abdominal CT scan revealed a large duodenal mass. Her gastrointestinal bleed was not amenable to endoscopic intervention, so she had emergent laparotomy, pancreaticoduodenectomy with duodenal mass excision. Histopathology confirmed that the duodenal mass was a metastatic deposit from her clear cell endometrial cancer. Postoperatively, she was frail and chose hospice care and she died 90 days postoperatively. Clear cell endometrial cancer is a rare subtype of endometrial cancer, that has a worse prognosis compared with the more common endometrioid subtype. The duodenum is a rare site for metastatic endometrial cancer, and we report this case to alert clinicians to the possibility of metastases to the small intestine in patients with clear cell endometrial cancer.

show abstract

A rare cause of intestinal bleeding: duodenal metastasis from endometrial cancer

Cited by 4 publications

References 3 publications

Small intestine metastasis from endometrial carcinoma initially presented as enterocutaneous fistula: a case report and literature review

Small intestine metastasis from endometrial carcinoma initially presented as enterocutaneous fistula: a case report and literature review

EUS-guided fine needle aspiration provides an open view for duodenal obstruction caused by urothelial carcinoma: a case report

Metastatic clear cell endometrial carcinoma: an unusual cause of a common clinical presentation

Contact Info

Product

Resources

About