Background: Primary cardiac angiosarcoma is a rare cardiac
tumor. Most of them grew in the right atrium, often invading the
superior vena cava and pericardium. The clinical symptoms of majority
patients may present right heart failure, superior vena cava
obstruction, and even pericardial tamponade. Case presentation:
In this case report, we presented a 76-year-old man presented with chest
tightness, fatigue, pericardial effusion, and arrhythmia. The
transthoracic echocardiography (TTE) showed that a mass in the right
atrium. Histopathology and immunohistochemistry confirmed the diagnosis
of angiosarcoma. The patient was discharged from hospital after surgery.
Conclusions: For the patients with early stage cardiac
angiosarcoma without evidence of metastasis, radical resection of the
primary tumor remains the most important approach for optimal survival.