A rare cause of adult's epileptic crisis: Infratentorial multinodular and vacuolating neuronal tumor

Abdelouahhab, H.; Guemmi, I.; Bouamama, T.; Kamaoui, I.; Nasri, S.; Aichouni, Narjiss; Skiker, I.

doi:10.1016/j.radcr.2022.08.006

Cited by 1 publication

(1 citation statement)

References 6 publications

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“…The vacuolar changes may be located in the cytoplasm or around the cell. Tumor cells are positive for SOX10, OLIG2, and HuC/HuD neuron-related markers, but NeuN is negative, indicating that these neuron-like cells may be immature neurons (8)(9)(10). Synaptophysin is expressed in the background glia of tumors but appears with light staining within the lesion nodules.…”

Section: Discussionmentioning

confidence: 99%

Case report: Rare case of multinodular and vacuolar neuronal tumors in the cerebellum

Wang,

2024

Front. Neurol.

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Multinodular and vacuolar neuronal tumor (MVNT) is a rare and benign neuroepithelial tumor. Most reports describe tumors located in the cerebral hemisphere. A literature review found that 15 cases were located in the posterior cranial fossa, but all lacked pathological evidence. In this case, a patient sought medical attention due to insomnia and irritability. Neuroepithelial tumors were found in the imaging, and the patient underwent radiation therapy. Three years later, malignant tumors were found upon imaging examination. After surgical resection and pathological testing, MVNT occurring in the cerebellum was diagnosed. MVNT is rare in the cerebellum, and direct imaging diagnosis becomes difficult after treatment. Therefore, our report of this case helps to further accurate understanding of the imaging, pathological, and molecular genetic changes occurring before and after MVNT treatment, and will improve the accuracy of pre-treatment diagnosis and reduce the likelihood of overtreatment.

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Section: Discussionmentioning

confidence: 99%

Case report: Rare case of multinodular and vacuolar neuronal tumors in the cerebellum

Wang,

2024

Front. Neurol.

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A rare cause of adult's epileptic crisis: Infratentorial multinodular and vacuolating neuronal tumor

Cited by 1 publication

References 6 publications

Case report: Rare case of multinodular and vacuolar neuronal tumors in the cerebellum

Case report: Rare case of multinodular and vacuolar neuronal tumors in the cerebellum

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