2013
DOI: 10.1038/aja.2013.88
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A rare case: paratesticular leiomyosarcoma

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Cited by 5 publications
(6 citation statements)
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“…2 There are no reported risk factors due to disease rarity, with approximately 100 cases reported in the literature. 3 Diagnosis is histology dependent, typically revealing spindle cells with 'cigar-shaped' nuclei arranged into interweaving fascicles. They are positive for actin and desmin on immunohistochemistry.…”
Section: Discussionmentioning
confidence: 99%
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“…2 There are no reported risk factors due to disease rarity, with approximately 100 cases reported in the literature. 3 Diagnosis is histology dependent, typically revealing spindle cells with 'cigar-shaped' nuclei arranged into interweaving fascicles. They are positive for actin and desmin on immunohistochemistry.…”
Section: Discussionmentioning
confidence: 99%
“…Haematological spread primarily results in lung metastases. 3 Radical inguinal orchidectomy with high ligation of the spermatic cord remains the accepted treatment. Simple excision is considered suboptimal, with repeat wide excision demonstrating residual disease in 27% of cases.…”
Section: Discussionmentioning
confidence: 99%
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“…Preoperative investigations should include scrotal ultrasound to assess the mass and its relation to the testis, however, histological analysis and immunochemical staining of tissue is required for diagnosis. 6 Once the diagnosis of leiomyosarcoma has been established by biopsy, clinical staging is necessary. Initial imaging should include plain radiographs of the affected area, computed tomography scan or magnetic resonance imaging of the abdominopelvic and inguinoscrotal regions, specifi cally looking for the presence of pelvic or retroperitoneal lymphadenopathy, which may be helpful in refi ning tumor location, as well as delineating the anatomic extent of the tumor.…”
Section: Discussionmentioning
confidence: 99%
“…Leiomyosarcoma is a malignant soft tissue tumor that can arise from any tissue containing smooth muscle. Leiomyosarcomas arising in paratesticular tissues are extremely rare and approximately 10% of all paratesticular sarcomas are leiomyosarcomas ( 1 ). Primary paratesticular tumors constitute 7% to 10% of all intrascrotal tumors ( 2 ).…”
Section: Introductionmentioning
confidence: 99%