A rare case of the superior vena cava obstruction in a 16-year-old boy with Burkitt's lymphoma: A case report

Abstract

Burkitt's lymphoma (BL) is an aggressive non-Hodgkin B-cell lymphoma. Superior vena cava obstruction (SVCO) is considered a rare presentation of BL and it is usually associated with other types of non-Hodgkin lymphoma such as diffuse large-cell. We report a rare case of sporadic BL with SVCO in a 16-year-old boy with nasopharyngeal, mediastinal, and adrenal masses. The patient presented with a two-month history of left upper neck swelling that increased with time and was not associated with other symptoms. The patient tested positive for COVID-19 on the second day after admission. On examination, he had enlarged solitary lateral cervical and bilateral posterior auricular lymph nodes. There were no signs or symptoms of SVCO regardless of the findings suggested by the computed tomography of the chest. The patient was treated with hyper-CVAD chemotherapy and showed a remarkable resolution of the nasopharyngeal and mediastinal masses with a mild response of his adrenal mass. There were no complications detected during this patient's management.

Blood cancer in children infected with COVID-19: A comprehensive systematic review

“…Last but not least, it is worth mentioning that most studies included in our review have reported to alter the intensity and regimen of anticancer treatment in blood cancer children during course of SARS-CoV-2 infection, however, many studies have reported to successfully treat COVID-19 in blood cancer children by proceeding with no changes to the anticancer treatment (13,23,25,31,32,38,57,58,63,64,76,78,81,87,90,105,115,117,118,128,156,157). Management of COVID-19 in children with blood cancer is limited and guidelines were largely based on adult data.…”