A Rare Case of Takotsubo Cardiomyopathy in a Patient With No Identifiable Emotional or Physical Stressors

Tin, Swann; Lim, William; Humayun, Anum; Galligan, Sean

doi:10.7759/cureus.17281

Cited by 1 publication

(2 citation statements)

References 14 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…However, only 0.001% of trauma incidents in the NTDB reported TTC from 2007 to 2018. This number is very low despite the association between physical triggers and the development of TTC [ 2 , 11 , 12 ], and it may be related to missed diagnoses, difficulty diagnosing TTC in the trauma population, or underreports of this important comorbidity in the NTDB. The number of diagnoses of TTC displayed over the years might be related to increasing awareness and changes in the diagnostic criteria over time [ 2 ] that could explain the up and down trending aspects of the distribution curve.…”

Section: Discussionmentioning

confidence: 99%

“…The diagnostic hallmark of TTC is its association with a stressful event. Although initial triggers were predominately limited to emotional trauma, recent evidence suggests TTC occurs with physical triggers or even in the absence of any recognizable stressors [ 2 , 11 , 12 ]. Potential physical stressors have been previously described, for example, surgical procedures, severe illnesses, fractures, dobutamine stress tests, electroconvulsive therapy, and cocaine use [ 1 ].…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Takotsubo Cardiomyopathy and Trauma: The Role of Injuries as Physical Stressors

Fernández¹,

Narveson²,

Walters³

et al. 2022

Cureus

View full text Add to dashboard Cite

Introduction: Physical stressors are common predisposing factors for takotsubo cardiomyopathy (TTC). However, the role of traumatic injuries in TTC has not been well defined. This study describes the characteristics of TTC in the broad spectrum of traumatic injuries using the information available in the National Trauma Data Bank (NTDB).Materials and methods: This retrospective study analyzed trauma patients ≥ 18 years old in the NTDB, from 2007 to 2018, with a diagnosis of TTC.Results: A total of 95 TTC diagnoses were found. The median age was 68 years old (interquartile range: 55-80). Patients were predominantly female (67.4%), white (88.4%), and sustained blunt mechanisms of injury (90.5%). Penetrating trauma was most common in males (16%). Most diagnoses were related to extremity trauma (53.7%), followed by head injury (26.3%). The most common severity scores were Glasgow Coma Scale (GCS) > 13 or < 8, and Injury Severity Score (ISS) < 15 or > 25. Males more commonly presented with GCS < 8 (68%), ISS > 25 (33%), high intensive care unit (ICU) admission rate (77.4%), and mechanical ventilation (51.6%). The median duration of the mechanical ventilation was eight days for both sexes. The ICU length of stay (LOS) was six days with a hospital LOS of nine days and a trend toward a longer LOS in males. The in-hospital mortality rate was 11.7% for both sexes.Conclusions: TTC in traumatic injuries is common at both ends of the severity spectrum and has different sex distribution. TTC patients are predominantly females and have more commonly extremity trauma than head injury. Males are more severely injured and under mechanical ventilation.

show abstract