A Rare Case of Severe Septic Shock in an Adult Secondary to Lysinibacillus Spahericus

Exit-Site Infection Caused by Lysinibacillus Sphaericus: Unusual Organism From A Usual Site

“…Our isolate was sensitive to cefuroxime which was used for seven days. In some cases, removal of the device responsible becomes important [8]. In our case, this was not required in our case as the patient responded to treatment.…”

“…In literature, Lysisnibacillus species have been reported to cause endophthalmitis [7]. L. sphaericus has been reported to cause bacteraemia in children with cancer or bone marrow transplant, neonates, neutropenic patients, injection drug users and has propensity towards surgically implanted catheters and chemotherapy ports [8]. L. fusiformis can cause tropical ulcers, severe sepsis and respiratory illnesses in humans [9].…”

“…Antibiotic susceptibility to this organism has been variable. Some isolates have been reported to be pan-sensitive while another case of infection by this organism was treated by ciprofloxacin [6,8]. Majority of Bacillus species show susceptibility to vancomycin, clindamycin, fluoroquinolones, aminoglycosides and carbapenems while variable susceptibility is seen to penicillin and cephalosporin [6].…”

Lysinebacillum Bacteriemia in an Adult Cancer patient

“…Lysinibacillus is a genus of rod-shaped gram-positive bacteria most often found in soil and plantlife, however, it has been isolated from air and from the human intestinal microbiome as well [1][2][3] . Lysinibacillus spp are very seldom associated with clinical disease.…”

“…Lysinibacillus spp are very seldom associated with clinical disease. However, there have been few reports of sepsis or other clinical conditions due to such organisms in humans 1,4,5 . Among relatively newly used microbiological identification techniques, mass spectroscopy pays an important role nowadays 6,7 .…”