“…4 D). Aetiologies include iatrogenic in 16 % (6 cases) [ [46] , [47] , [48] , [49] , [50] ], valvular heart disease in 14 % (5 cases) [ [51] , [52] , [53] ], trauma in 11 % (4 cases) [ 54 , 55 ], cancer in 11 % (4 cases) [ 56 , 57 ], infectious disease in 5 % (2 cases) [ 4 , 58 ], and other more rare complication of conditions, as pregnancy [ 59 ], Takayasu's arteritis [ 60 ], idiopathic pulmonary artery dilatation [ 61 ], amyloidosis, hypergammaglobulinemia of unknown cause and obesity [ 4 ], and others [ [62] , [63] , [64] , [65] , [66] ]. The diversity of the underlying aetiology suggests that triggers other than pulmonary hypertension may also lead to pulmonary artery degeneration and result in PAD.…”