A rare case of primary invasive carcinoma of vagina associated with irreducible third degree uterovaginal prolapse

Gupta, Nupur; Mittal, Suneeta; Dalmia, S.; Misra, Renu

doi:10.1007/s00404-007-0415-4

Cited by 18 publications

(19 citation statements)

References 4 publications

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“…The tumor usually arises on the posterior wall of the upper third of vagina, and epidermoid carcinoma is the most common histological type observed [3,4,5,6]. Until recently, approximately 10 cases were reported on primary vaginal cancer complicated by uterine prolapse [4,6,7,8,9](table 1). It is usually squamous carcinoma and occurs in the upper third of vagina.…”

Section: Discussionmentioning

confidence: 99%

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Uterine Prolapse Complicated by Vaginal Cancer: A Case Report and Literature Review

Wang¹,

Li²,

et al. 2014

Gynecol Obstet Invest

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Primary vaginal cancer is not common, representing 1-2% of all female genital malignancies. We present a case of a third-degree uterine prolapse complicated by an isolated primary vaginal cancer and its surgical treatment. The cervix was clinically normal, but on the nearby prolapsed vaginal wall, a large exogenous hard lesion had developed. A biopsy of the lesion revealed a squamous carcinoma. The patient was asymptomatic and had no recurrence during the last 4 years of follow-up after surgical treatment with radiotherapy. The surgical treatment with or without radiotherapy is the optimum treatment for uterine prolapse with early-stage vaginal squamous cell carcinoma, although the majority of vaginal malignancies are treated with radiotherapy. We recommend always performing a biopsy prior to surgery in prolapse-induced ulceration.

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Section: Discussionmentioning

confidence: 99%

“…It is usually squamous carcinoma and occurs in the upper third of vagina. Risk factors for developing vaginal carcinoma are associated with bacterial infection, trauma (especially after pessary or prolapse), and HPV exposure [7]. …”

Section: Discussionmentioning

confidence: 99%

Uterine Prolapse Complicated by Vaginal Cancer: A Case Report and Literature Review

Wang¹,

Li²,

et al. 2014

Gynecol Obstet Invest

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“…This malignancy has also been found in patients with vaginal or utero-vaginal prolapse [23][24][25]. Anecdotal cases have been described in women who had undergone vaginoplasty for vaginal agenesis due to Rokitansky-Kuster-Hauser syndrome [26][27][28].…”

Section: Epidemiology Risk Factors and Natural Historymentioning

confidence: 99%

Squamous cell carcinoma of the vagina: natural history, treatment modalities and prognostic factors

Gadducci

Fabrini

Lanfredini

et al. 2015

Critical Reviews in Oncology/Hematology

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“…Five years survival is 80% if diagnosed in fi rst stage as compared to 35-50, 35 and 20% in Stage II, III and IV respectively. 7 In conclusion, biopsy should be taken from a long standing ulcer in an uterovaginal prolapse as there is always a potential chance of malignancy. She was then referred to cancer hospital for radiotherapy and further management.…”

Section: Case Reportmentioning

confidence: 99%

Carcinoma of Vagina in Utero-Vaginal Prolapse: A Rare Presentation

Acharya

Uprety

2012

J Nepal Med Assoc

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Primary vaginal carcinoma in uterovaginal prolapse is a rare entity. We report a case of an 84-years-old lady, who presented with long standing vaginal ulcer in association with third degree uterovaginal prolapse. Incisional biopsy was taken from the ulcer. Histopathological examination showed a large cell keratinizing squamous cell carcinoma. Keywords: Squamous cell carcinoma, uterovaginal prolapse, vaginal carcinoma.

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A rare case of primary invasive carcinoma of vagina associated with irreducible third degree uterovaginal prolapse

Cited by 18 publications

References 4 publications

Uterine Prolapse Complicated by Vaginal Cancer: A Case Report and Literature Review

Uterine Prolapse Complicated by Vaginal Cancer: A Case Report and Literature Review

Squamous cell carcinoma of the vagina: natural history, treatment modalities and prognostic factors

Carcinoma of Vagina in Utero-Vaginal Prolapse: A Rare Presentation

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