A rare case of pemphigus herpetiformis in a young woman

Pasquale, Rocco De; Scuderi, Laura; Caltabiano, Rosario; Russo, G.; D’Urso, Diego; Condorelli, Alessandra Grazia

doi:10.23736/s0392-0488.18.05866-2

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2023

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“…Fibrosarcomatous change in DFSP is a form of tumor progression that carries an increased risk of metastases [ 3 ]. The origin of DFSP is unknown [ 4 ]. The treatment of DFSP is generally surgical, and wide local excision is the mainstay of surgical treatment [ 5 , 6 ].…”

Section: Discussionmentioning

confidence: 99%

Dermatofibrosarcoma Protuberans (DFSP) with Fibrosarcomatous Changes in a Patient with Crohn’s Disease Treated with Anti-TNF (Adalimumab)

Klarin

2023

Case Reports in Gastrointestinal Medicine

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Dermatofibrosarcoma protuberans (DFSP) is a low-to-intermediate grade sarcoma with a reported incidence of 4.1 per million person-years. Despite its local invasiveness, it rarely metastasizes (5% of cases). Fibrosarcomatous change in DFSP is a form of tumor progression that carries an increased risk of metastases. We reported a case of 45-year-old patient treated with adalimumab lasting 7 years for Crohn’s disease who developed dermatofibrosarcoma protuberans with fibromatous changes. Adalimumab therapy was stopped before surgery, and ustekinumab was introduced 6 months after.

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Section: Discussionmentioning

confidence: 99%

A rare case of pemphigus herpetiformis in a young woman

Cited by 1 publication

References 5 publications

Dermatofibrosarcoma Protuberans (DFSP) with Fibrosarcomatous Changes in a Patient with Crohn’s Disease Treated with Anti-TNF (Adalimumab)

Dermatofibrosarcoma Protuberans (DFSP) with Fibrosarcomatous Changes in a Patient with Crohn’s Disease Treated with Anti-TNF (Adalimumab)

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