A rare case of osteoblastoma associated to aneurysmal bone cyst of the spine. Case report

Pavanello, Marco; Melloni, Ilaria; Fiaschi, Pietro; Consales, Alessandro; Piatelli, Gianluca; Ravegnani, Marcello; Nozza, Paolo; Cama, Armando

doi:10.3109/02688697.2015.1071332

Cited by 14 publications

(25 citation statements)

References 3 publications

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“…Another, similar case was reported in an 11-year-old boy at the C4 level by Hu et al [9]. Pavanello et al [10] reported a similar pathology in the lumbar region (L2 level).…”

Section: Discussionsupporting

confidence: 48%

Cervical Spine Osteoblastoma with an Aneurysmal Bone Cyst in a 2-Year-Old Child: A Case Report

et al. 2019

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Osteoblastomas and aneurysmal bone cysts are uncommon benign tumors of the spine. Their presentation can vary between diffuse pain, restriction of neck movements, torticollis, radiculopathy, and myelopathy. Complete excision is the best treatment to achieve a cure, but recurrence is not uncommon. A combination of the two conditions in the pediatric population is extremely rare. To the best of the authors’ knowledge, only 2 cases of such a combination in the cervical spine have been reported in the literature. We report the case of a 2-year-old child having a right C4 lateral mass osteoblastoma with an aneurysmal bone cyst. The child underwent complete surgical excision of the lesion with fusion.

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“…Another, similar case was reported in an 11-year-old boy at the C4 level by Hu et al [9]. Pavanello et al [10] reported a similar pathology in the lumbar region (L2 level).…”

Section: Discussionsupporting

confidence: 48%

Cervical Spine Osteoblastoma with an Aneurysmal Bone Cyst in a 2-Year-Old Child: A Case Report

et al. 2019

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“…Components of aneurysmal bone cysts are reported to be present in approximately 10%-15% of cases of osteoblastomas. 34,40,60,70,73,93 This finding may confound the final pathology findings. Osteoid osteoma transitioning to an osteoblastoma has been reported in the literature, although this not a common occurrence.…”

Section: Pathologymentioning

confidence: 81%

Osteoblastomas of the spine: a comprehensive review

Galgano¹,

Goulart²,

Iwenofu

et al. 2016

FOC

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Osteoblastomas are primary bone tumors with an affinity for the spine. They typically involve the posterior elements, although extension through the pedicles into the vertebral body is not uncommon. Histologically, they are usually indistinguishable from osteoid osteomas. However, there are different variants of osteoblastomas, with the more aggressive type causing more pronounced bone destruction, soft-tissue infiltration, and epidural extension. A bone scan is the most sensitive radiographic examination used to evaluate osteoblastomas. These osseous neoplasms usually present in the 2nd decade of life with dull aching pain, which is difficult to localize. At times, they can present with a painful scoliosis, which usually resolves if the osteoblastoma is resected in a timely fashion. Neurological manifestations such as radiculopathy or myelopathy do occur as well, most commonly when there is mass effect on nerve roots or the spinal cord itself. The mainstay of treatment involves surgical intervention. Curettage has been a surgical option, although marginal excision or wide en bloc resection are preferred options. Adjuvant radiotherapy and chemotherapy are generally not undertaken, although some have advocated their use after less aggressive surgical maneuvers or with residual tumor. In this manuscript, the authors have aimed to systematically review the literature and to put forth an extensive, comprehensive overview of this rare osseous tumor.

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“…We found four cases of spinal osteoblastoma associated with secondary ABC in recently published studies. Three of these involved the cervical spine and one originated in lumbar vertebra [2][3][4][5] ( Table 1). Osteoblastoma combined with ABC in the spinal column has a high rate of recurrence if incomplete resection is done [11,12].…”

Section: Discussionmentioning

confidence: 99%

“…We report a case with histologically proven osteoblastoma associated with secondary ABC arising from C4 cervical vertebra and eroding into adjacent vertebrae with a 2-year follow-up. To our knowledge, only four such cases have been documented in recent literature [2][3][4][5]. Early and correct diagnosis and complete removal can be a challenge given a protracted clinical presentation and cervical location that makes achieving a clean margin difficult.…”

Section: Introductionmentioning

confidence: 99%

C4 cervical spine osteoblastoma associated with secondary aneurysmal bone cyst in an adolescent patient: 2-year follow-up

Gahlot

Jalan

Elhence

2019

Spinal Cord Ser Cases

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Introduction Osteoblastoma and aneurysmal bone cyst (ABC) are rare bone tumors with individual prevalence of <1%. Their combined occurrence is a rare subclass of tumors in the spinal column with only a few cases reported in literature. Case presentation The present case is a rare combination of aggressive osteoblastoma with secondary aneurysmal bone cyst masquerading as neck pain, arising from cervical C4 vertebra in a 19-year-old male. The patient presented with complaints of neck pain for 7 months, gradual in onset, dull, aching, and progressively increasing in severity. Neurological examination was normal. Radiology showed an expansile lytic mass arising from the posterior elements of C4 vertebra involving the left lateral mass. Piecemeal total removal was done and a posterior fusion from C3 to C5 was performed for stability. Histopathology confirmed the osteoblastoma with a secondary aneurysmal bone cyst. Postoperatively the patient recovered well, and no recurrence was seen on a 2-year follow-up. Discussion Simultaneous presence of an osteoblastoma with a secondary ABC arising from various bones, such as cranial fossa, ethmoid sinus, skull, and mandibular condyle, has rarely been reported. It is often diagnosed late due to nonspecific symptoms; but it has a good prognosis if early and complete resection is performed. Thorough surgical excision is always a challenge in spine cases due to surrounding important structures and meticulousness is required to prevent any recurrences. Hence, we recommend a surgical team comprising both spine and musculoskeletal oncologic surgeons to achieve best results.

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A rare case of osteoblastoma associated to aneurysmal bone cyst of the spine. Case report

Cited by 14 publications

References 3 publications

Cervical Spine Osteoblastoma with an Aneurysmal Bone Cyst in a 2-Year-Old Child: A Case Report

Cervical Spine Osteoblastoma with an Aneurysmal Bone Cyst in a 2-Year-Old Child: A Case Report

Osteoblastomas of the spine: a comprehensive review

C4 cervical spine osteoblastoma associated with secondary aneurysmal bone cyst in an adolescent patient: 2-year follow-up

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