A rare case of meningitis and septicemia caused by Streptococcus suis in a woman without a history of live pig contact or eating raw pork

Zhu, Yu; Zhu, Fang; LiHong, Bo; Fang, Yinfei; Shan, Xin

doi:10.1007/s42770-021-00619-8

Cited by 6 publications

(9 citation statements)

References 24 publications

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“…[9] According to 1 meta-analysis, among 648 patients infected with S suis, 395 (61%) had a history of contact with pigs or pork. [10] A case of suppurative encephalitis caused by S suis has been reported in Japan. The patient was a chef with hand wounds, suggesting that the infection was due to contact with raw pork and that bacteria might have entered his body through his hand wounds.…”

Section: Discussionmentioning

confidence: 99%

Meningitis and sepsis caused by Streptococcus suis in an elderly woman: A CARE-compliant case report

Li,

Hong

et al. 2023

Medicine

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Rationale: Streptococcus suis (S suis)-associated infections are uncommon but life-threatening diseases. The clinical manifestations vary from general symptoms of bacterial infection to fatal meningitis. The clinical manifestation and routine diagnostic testing is not specific enough to obtain well-time diagnosis. Patient concerns and diagnosis: We report a case of meningitis and sepsis caused by S suis infection. A 70-year-old woman presented to our emergency department with generalized pain. After hospital admission, her condition rapidly deteriorated to fever, intracranial hypertension, and disturbance of consciousness. Examination of the blood and cerebrospinal fluid with metagenomic next-generation sequencing and bacterial cultures revealed S suis infection. Interventions and outcomes: After anti-infection therapy with meropenem and vancomycin, the patient recovered and was discharged from the hospital with no residual effects. Lessons: Human infections with S suis are extremely rare. If clinicians encounter a patient with fever, disturbance of consciousness, and intracranial hypertension, especially those who have been exposed to raw pork, S suis infection should be considered. Metagenomic next-generation sequencing can be a useful adjunct for the rapid diagnosis of S suis infection and aid in the planning of clinical treatment. Meanwhile, public health awareness is necessary to limit the risk of S suis infection.

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Section: Discussionmentioning

confidence: 99%

Meningitis and sepsis caused by Streptococcus suis in an elderly woman: A CARE-compliant case report

Li,

Hong

et al. 2023

Medicine

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“…In the outbreaks of S. suis infection that occurred in China, almost all the human patients had a history of direct contact with infected pigs or pork [ 3 ]. However, there are several cases that develop S. suis infection without known history of pig contact [ 14 , 15 ]. As with many bacterial infections, the confirmation of S. suis infection relies on the isolation of the infectious agent from normally sterile body fluid, including blood and cerebrospinal fluid.…”

Section: Discussionmentioning

confidence: 99%

Spinal canal infection caused by Streptococcus suis in human: a case report

Wang

Lei

et al. 2022

BMC Infect Dis

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Background Streptococcus suis is an emerging zoonotic pathogen that mainly causes meningitis, sepsis, arthritis, endocarditis, and endophthalmitis in human. To the best of our knowledge, Spinal canal infection caused by Streptococcus suis has rarely been reported. Case presentation Here we report a case of spinal canal infection caused by Streptococcus suis in a 50-year-old male patient. The patient had a history of close contact with sick pigs days before disease onset. Initially he presented with headache and fever. After admission, the patient began to experience lower back pain, which led physicians to perform a lumber puncture. Meta-genomic next generation sequencing helped identify Streptococcus suis in the cerebrospinal fluid. MRI imaging indicated a spinal canal infection caused by Streptococcus suis. Conclusions Spinal canal infection is an uncommon disease of Streptococcus suis infection. This case report indicates that people presented with fever, headache and lower back pain should also be suspected as Streptococcus suis infection, especially for those who have had a history of sick pig contact.

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“…Although Russia has a highly developed pig-rearing business, human infection is almost nonexistent, uncommon in North America, less common in northern Europe, and quite common in Southeast Asia [2] . S. suis can colonize the upper respiratory system, particularly the tonsils and nasal cavities, as well as the digestive and genital tracts in healthy pigs [1] . Between 2016 and 2018, Zhang et al.…”

Section: Discussionmentioning

confidence: 99%

“…Streptococcus suis (S. suis) is a zoonotic pathogen that causes pneumonia, sepsis, endocarditis, and meningitis [1 , 2] . S. suis is primarily found in the upper respiratory tract of pigs [3 , 4] , and infection was initially documented in pigs in 1954, followed by the first human case in Denmark in 1968 [5] .…”

Section: Introductionmentioning

confidence: 99%