A rare case of melioidosis presenting as pericarditis and pneumonia in a patient with poorly controlled diabetes mellitus

Abstract

Melioidosis is a rare but often fatal tropical infection caused by gram-negative bacteria Burkholderia pseudomallei. It most commonly manifests as pneumonia and rarely presents as pericarditis. Melioidosis can be difficult to diagnose because of its diverse clinical manifestation and close resemblance to bacteria of the genus Pseudomonas. We report a rare case of melioidosis presenting as pericarditis and pneumonia in a 61-year-old male patient with poorly controlled diabetes mellitus. He was initially misdiagnosed with Pseudomonas aeruginosa infection and later treated empirically as tuberculosis pericarditis for 2 months, before reaching the diagnosis of melioidosis.

In-silico Prediction of Drug Target, Molecular Modeling, and Docking Study of Potential Inhibitors against Burkholderia pseudomallei

“…Continuous exposure to infected soils and groundwater leads to an increased risk of causing melioidosis. Pneumonia is the most common symptom of melioidosis, observed in half of all cases (Leung et al, 2023). The seriousness of the disease varies widely, such as illness with high fever, tiny cough, inflamed pain, and difficulty breathing (Khattab et al, 2022).…”