A rare case of invasive vaginal carcinoma associated with vaginal prolapse

Batista, Thales Paulo; Morais, José Alves; Reis, Tarcísio José Cysneiros Costa; Macedo, Francisco Igor B.

doi:10.1007/s00404-009-1016-1

Cited by 15 publications

(14 citation statements)

References 8 publications

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“…This malignancy has also been found in patients with vaginal or utero-vaginal prolapse [23][24][25]. Anecdotal cases have been described in women who had undergone vaginoplasty for vaginal agenesis due to Rokitansky-Kuster-Hauser syndrome [26][27][28].…”

Section: Epidemiology Risk Factors and Natural Historymentioning

confidence: 99%

Squamous cell carcinoma of the vagina: natural history, treatment modalities and prognostic factors

Gadducci

Fabrini

Lanfredini

et al. 2015

Critical Reviews in Oncology/Hematology

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Section: Epidemiology Risk Factors and Natural Historymentioning

confidence: 99%

Squamous cell carcinoma of the vagina: natural history, treatment modalities and prognostic factors

Gadducci

Fabrini

Lanfredini

et al. 2015

Critical Reviews in Oncology/Hematology

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“…Vaginal trauma, chronic irritation, and inflammation of the vaginal mucosa can cause primary vaginal cancer in patients with POP [3]. However, a combination of POP and primary vaginal or cervical cancer is an extremely rare entity [4,5,6,7,8,9,10,11,12,13,14,15,16,17,18,19].…”

Section: Purposementioning

confidence: 99%

Using a pessary during radiotherapy in reducible pelvic organ prolapse and vaginal cancer: a case report and review of the literature

Gültekin

Esen

Akgör

et al. 2020

jcb

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Purpose: Primary vaginal cancer and pelvic organ prolapse (POP) combination is extremely rare. Although definitive chemoradiotherapy (CRT) and brachytherapy (BT) is the standard treatment for advanced stage primary vaginal cancer, there is a limited data about the treatment of primary vaginal cancer combined with POP due to its rarity. In addition, radiotherapy (RT) process may be difficult in these cases and often result in more toxicity. Case presentation: In this case report, we present a 77-year-old woman with a diagnosis of primary vaginal cancer associated with POP, who was treated with definitive CRT using a pessary to restore vaginal anatomy for optimal radiation. Following CRT, complete response was observed and vaginal cuff BT was performed. The patient tolerated the treatment very well and is still alive without disease at 10-months follow-up. Conclusions: Combined primary vaginal cancer and POP is an extremely rare clinical entity, with only a few cases reported in the literature. When applying CRT in these cases, critical organ doses may be higher than expected due to the downward descent of the pelvic organs. Especially in elderly patients, a pessary can be used as a non-surgical procedure to restore the anatomy for symptom relief during definitive CRT. Additionally, it allows tumors to be targeted more precisely.

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“…Primary vaginal carcinoma is rare and comprises only one to two percent of all gynecologic malignancies 1 with its incidence peak during the sixth decade. 2 The development of carcinoma of vagina in the ulcerated part of the uterovaginal prolapse is a rare entity described in the English literature. Herein, we present a case of an early stage of vaginal carcinoma developed in the long standing uterovaginal prolapse with review of the related literature.…”

Section: Introductionmentioning

confidence: 99%

Carcinoma of Vagina in Utero-Vaginal Prolapse: A Rare Presentation

Acharya

Uprety

2012

J Nepal Med Assoc

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Primary vaginal carcinoma in uterovaginal prolapse is a rare entity. We report a case of an 84-years-old lady, who presented with long standing vaginal ulcer in association with third degree uterovaginal prolapse. Incisional biopsy was taken from the ulcer. Histopathological examination showed a large cell keratinizing squamous cell carcinoma. Keywords: Squamous cell carcinoma, uterovaginal prolapse, vaginal carcinoma.

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A rare case of invasive vaginal carcinoma associated with vaginal prolapse

Cited by 15 publications

References 8 publications

Squamous cell carcinoma of the vagina: natural history, treatment modalities and prognostic factors

Squamous cell carcinoma of the vagina: natural history, treatment modalities and prognostic factors

Using a pessary during radiotherapy in reducible pelvic organ prolapse and vaginal cancer: a case report and review of the literature

Carcinoma of Vagina in Utero-Vaginal Prolapse: A Rare Presentation

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