A Rare Case of Granulosa Cell Tumor Associated With Endometrial Carcinoma - A Case Report

Abstract

Adult granulosa cell tumors are uncommon ovarian tumors mainly diagnosed after the age of 30, and the average age is roughly 55. Very few cases are associated with endometrial carcinoma. Most of these cases are well-differentiated endometrioid adenocarcinoma with excellent prognosis if found early. Heavy, irregular menstrual bleeding and postmenopausal bleeding are frequent and are caused by endometrial shedding due to unopposed estrogen action for a prolonged period of time.A 65-year-old female para 4, live 4 (P4L4) came with postmenopausal bleeding for six months. Various investigations were done, which revealed endometrial cancer type 1. A staging laparotomy was performed, which showed a right hemorrhagic ovarian mass; on a frozen section, it came to be a granulosa cell tumor.The rare association between granulosa cell tumor and endometrial carcinoma can be diagnosed with a good correlation of clinical, histopathological, and radiological findings.

Clinical Utility of Diffusion-Weighted Imaging in Gynecological Imaging

“…Meanwhile, 25%-30% of the patients with adult granulosa cell tumors coexist with endometrial hyperplasia or endometrial cancer due to estrogen production from the tumor. 30 Therefore, granulosa cell tumors should also be considered as a differential diagnosis in postmenopausal women with uterine enlargement. Such incidental small granulosa cell tumors are difficult to diagnose with conventional MRI but are clearly depicted on DWI (Fig.…”