A rare case of gliomatosis cerebri presenting as dementia

Abstract

Dementia with the onset before the age of 65 years is classified as early-onset dementia. Although uncommon, it has considerable impact on the lives of patients and care givers, alike. A substantial subset of patients may have underlying reversible causes. Yet, many, especially those of the very young may be initially misdiagnosed. A case of young woman with rapid mental decay is described here. She was finally diagnosed with gliomatosis cerebri (GC) involving only right frontal lobe. This atypical radiological feature of GC with primary presentation as memory loss needs special attention and clinicians should be aware of such conditions.

Yüksek greydli gliomatozis serebri olgusu; MR, Diffüzyon MR ve MR spektroskopi bulguları

“…Ayrıca bu çalışmada baş ağrısı %39, nöbet %38, kranial nöropati %37, intrakranial basınç artışı %34 ve spinoserebellar defisit %33 sıklığında bildirilmiştir (1). Literatürde demans kliniği ile başvuran olgularda mevcuttur (6). Bizim olgumuz da kortikospinal trakt bulguları, bilinç değişiklikleri, mental fonksiyonlarda azalma ve fasial paralizi mevcuttu.…”

CASE REPORT: An Indolent Presentation of Gliomatosis Cerebri in an Elderly Patient: Posterior Fossa Decompression Prior to Treatment

“…Gutch, et al reported that the clinical course of GC is typically slow and long, especially when the neoplastic infiltrate is of low histological grade [9].…”