A rare case of enteric and systemic Yersinia enterocolitica infection in a chronic, not iron-overloaded dialysis patient

Abstract

SummaryWe present herein a case of bacterial gastroenteritis due to Yersinia enterocolitica, occurred in a young woman undergoing haemodialysis with a previous history positive for prolonged (20 years) immunosuppressive therapy for glomerulonephritis before and for kidney transplant later. The patient's outcome was favourable after a third-generation cephalosporin treatment without complications. The possible pathophysiological association between patient clinical condition and Yersinia bacteraemia is discussed, along with the review of literature.

Pemphigus foliaceus complicated by sepsis of the aetiology of Yersinia enterocolitica after eating cheesecake

“…Although the incidence is very low [15], it is a serious problem due to a death rate of about 30% [23,24]. It is necessary to apply antibiotic therapy when a generalised infection is diagnosed [6]. In our case report, the bacterial strain was sensitive to most of the antibiotics applied.…”

“…Yersinia spp. may cause severe illness in patients with immunodeficiency [6,7], like in the case of a patient with pemphigus foliaceus who developed sepsis. Recent observations have shown that the percentage of generalised infections caused by Yersinia spp.…”

Yersinia enterocolitica Infection in Patients Undergoing Intermittent Hemodialysis

“…Most HD patients infected by YE were found to be overloaded with Fe (52)(53)(54)(55). However, there is also a report of an HD patient infected with YE without being overloaded with Fe (56). Some studies have suggested that ESA therapy might help in the treatment of YE, as it lowers serum ferritin and transferrin saturation, and improves phagocytosis (57)(58)(59).…”

“…Septicemia due to YE infection has been reported sporadically. Some reported cases were associated with the administration of deferoxamine (60-62), and one case was reported due to eating undercooked meat (56). Table 1 summarizes the reported YE infections in HD patients.…”