A Rare Case of Cutaneous Plasmacytosis in a Korean Male

Georgesen, Corey; Kheterpal, Meenal; Pulitzer, Melissa

doi:10.1155/2017/3032941

Cited by 6 publications

(5 citation statements)

References 20 publications

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“…Almost all reported patients have been Japanese adult males, with few reported cases of Chinese, Thai, and White patients. [135][136][137][138][139][140] The disease commonly presents with lymphadenopathy, hypergammaglobulinemia, and asymptomatic red-brown macules or plaques of the face, neck, or trunk. 141 Histopathologic findings include dense dermal infiltrates of mature polyclonal plasma cells with peri-vascular, peri-neural, and periadnexal infiltration (Figure 17).…”

Section: Cutaneous Plasmacytosismentioning

confidence: 99%

“…Cutaneous plasmacytosis is rare, with under 100 reported cases. Almost all reported patients have been Japanese adult males, with few reported cases of Chinese, Thai, and White patients 135–140 . The disease commonly presents with lymphadenopathy, hypergammaglobulinemia, and asymptomatic red‐brown macules or plaques of the face, neck, or trunk 141 .…”

Section: Non‐neoplastic Inflammatory Conditions With Clhmentioning

confidence: 99%

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Cutaneous reactive B‐cell lymphoid proliferations

Khalil

Donthi²,

Gru

2022

J Cutan Pathol

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Cutaneous lymphoid hyperplasia (CLH), also known as cutaneous pseudolymphoma, is a spectrum of benign conditions characterized by reactive B‐ and T‐cell cutaneous lymphocytic infiltrates. B‐cell lymphoid proliferations are a heterogenous group of non‐neoplastic cutaneous diseases that must be histopathologically distinguished from cutaneous B‐cell lymphomas. These proliferations can be observed as reactive phenomena to infections, medications, allergens, neoplasms, and more. Furthermore, there are many inflammatory conditions that present with reactive B‐cell infiltrates, including actinic prurigo, Zoon balanitis, Rosai‐Dorfman disease, and cutaneous plasmacytosis. This review summarizes multiple cutaneous B‐cell lymphoid proliferations within the major categories of reactive and disease‐associated CLH. Further we discuss major discriminating features of atypical CLH and malignancy. Understanding the specific patterns of B‐cell CLH is essential for the proper diagnosis and treatment of patients presenting with such lesions.

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Section: Cutaneous Plasmacytosismentioning

confidence: 99%

Section: Non‐neoplastic Inflammatory Conditions With Clhmentioning

confidence: 99%

Cutaneous reactive B‐cell lymphoid proliferations

Khalil

Donthi²,

Gru

2022

J Cutan Pathol

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“…Since then, multiple terms were introduced including plasmacytosis mucosae, plasma cell orificial mucositis, plasma cell mucositis, and MMP, however no consensus in terminology still exists. Exceedingly rare cases of cutaneous and systemic variants of plasmacytosis have been reported in patients of Asian descent but appear to be unrelated to MMP [10].…”

Section: Introductionmentioning

confidence: 99%

Laryngeal mucous membrane plasmacytosis with 15 year follow-up: Case report and literature review

Makarenko

Vaezi

Brettler

et al. 2020

Leukemia Research Reports

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Mucous membrane plasmacytosis (MMP) is an uncommon variant of mucositis represented by a polyclonal plasma cell infiltration of mucosal tissue. Various clinical presentations in the upper airway have been reported ranging from erythematous mucosa to fungating masses. Histologic features include mucosal epithelial hyperplasia or psoriasiform changes with a dense submucosal infiltrate of polytypic plasma cells. Molecular studies for immunoglobulin gene rearrangement should be performed in all cases of MMP to rule out clonal neoplastic expansion of plasma cells. We present a case of MMP with over 15 years of clinical follow-up, emphasizing the relatively benign clinical course of this disorder.

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“…Cutaneous plasmacytosis mainly affects adult Asian males and is characterized clinically by widespread non‐scaly, erythematous/brown plaques on the trunk and head/neck. Microscopically the lesions display mature, polytypic, plasma cell‐rich cutaneous infiltrates in perivascular, interstitial and perineural distributions.…”

Section: Plasmacytic Infiltrates In the Skin—inflammatorymentioning

confidence: 99%

“…This has prompted use of the term “cutaneous and systemic plasmacytosis”. A potential to evolve to lymphoma has been postulated …”

Section: Plasmacytic Infiltrates In the Skin—inflammatorymentioning

confidence: 99%

Plasmacytic cutaneous pathology: A review

et al. 2019

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We review the spectrum of cutaneous disorders associated with inflammatory and neoplastic plasmacytic pathology. Because plasma cells are derived from B‐lymphocytes our overview includes discussion of certain lymphoplasmacytic proliferations. It is structured along histopathological lines, addressing conditions characterized by (a) cutaneous plasma cell infiltrates, (b) deposits of plasma cell products or their derivatives in the skin and (c) miscellaneous, poorly understood cutaneous complications of plasmacytic disorders. Lesions arising primarily in the skin and those due to cutaneous involvement by multisystem disorders are addressed. The range includes a spectrum of tumefactive and circulatory manifestations. We highlight key clinical and pathological features of the different conditions and outline recent advances in our understanding of these entities. By emphasizing the dermatopathological characteristics of this spectrum of disorders we hope to hone the diagnostic accuracy of practitioners in the field.

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A Rare Case of Cutaneous Plasmacytosis in a Korean Male

Cited by 6 publications

References 20 publications

Cutaneous reactive B‐cell lymphoid proliferations

Cutaneous reactive B‐cell lymphoid proliferations

Laryngeal mucous membrane plasmacytosis with 15 year follow-up: Case report and literature review

Plasmacytic cutaneous pathology: A review

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