A rare case of cade oil poisoning complicated by acute pancreatitis and acute tubular necrosis

Azizi, Mohammed; Kaouini, Abderrahim El; Lafkih, Mohammed Amine; Bouayed, Zakaria; Bkiyar, Houssam; Housni, Brahim

doi:10.1016/j.amsu.2022.103562

Cited by 4 publications

(4 citation statements)

References 3 publications

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“…N-acetylcysteine may be recommended to prevent the accumulation of free radicals due to hepatic biotransformation and to bind toxic metabolites. If methemoglobinemia develops, methylene blue can be administered (6).…”

Section: Discussionmentioning

confidence: 99%

“…It has been utilized in traditional folk medicine to treat a range of ailments, including hyperglycemia, obesity, tuberculosis, bronchitis, pneumonia, kidney stones, and the management of various dermatological conditions (3). Despite its historical use, there is a scarcity of documented cases regarding the potential complications associated with Juniper Tar, some of which have been fatal (4)(5)(6)(7)(8). Considering the widespread availability of Juniper Tar in Mediterranean countries, it is essential to emphasize the need for increased awareness among emergency physicians regarding its toxic effects.…”

Section: Introductionmentioning

confidence: 99%

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Acute Systemic Toxicity Associated with Ingestion of Juniper Tar

ÖZDAMAR,

DEMİR

2023

Journal of Emergency Medicine Case Reports

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ABSTRACT Introduction: Juniper Tar has been utilized in traditional folk medicine to treat various ailments. Despite its historical use, documented cases are scarce regarding the potential complications associated with Juniper Tar, some of which have been fatal. Case Report: A 62-year-old male patient with no previous medical history presented to the emergency department complaining of confusion and respiratory distress after drinking a glass of Juniper Tar approximately four hours ago. The patient, who experienced multiple seizures and cardiac arrest at the emergency department, was discharged after an 11-day intensive care unit monitoring period. Conclusion: We present this case to raise awareness among emergency physicians about Juniper Tar, which is widely used for various purposes in folk medicine and cosmetics but can cause poisoning due to its content of essential oils, triterpenes, and phenols. This is a case of cardiac arrest and status epilepticus associated with juniper tar poisoning. Keywords: Juniper tar; toxicity; emergency department

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Acute Systemic Toxicity Associated with Ingestion of Juniper Tar

ÖZDAMAR,

DEMİR

2023

Journal of Emergency Medicine Case Reports

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“…The essential oils derived from the Juniperus species exhibit a diverse range of pharmacological properties. Nevertheless, it is crucial to highlight that there have been numerous reported cases of intoxication associated with cade oil, obtained from the branches of Juniperus oxycedrus L. (Cupressaceae) [289][290][291]. Phenol, a constituent of cade oil, can exert adverse effects on various organ systems, including the central and peripheral nervous systems, cardiovascular system, liver and biliary systems, skin, and respiratory system [291].…”

Section: Toxicological Evidencementioning

confidence: 99%

Therapeutics to Treat Psychiatric and Neurological Disorders: A Promising Perspective from Algerian Traditional Medicine

Larit,

León

2023

Plants

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Ancient people sought out drugs in nature to prevent, cure, and treat their diseases, including mental illnesses. Plants were their primary source for meeting their healthcare needs. In Algeria, folk medicine remains a fundamental part of the local intangible knowledge. This study aims to conduct a comprehensive ethnomedicinal investigation and documentation of medicinal plants and the different plant formulations traditionally used in Algeria for the treatment of pain, psychiatric, and neurological disorders. It also intends to improve the current knowledge of Algerian folk medicine. Several scientific databases were used to accomplish this work. Based on this investigation, we identified 82 plant species belonging to 69 genera and spanning 38 distinct botanical families used as remedies to treat various psychological and neurological conditions. Their traditional uses and methods of preparation, along with their phytochemical composition, main bioactive constituents, and toxicity were noted. Therefore, this review provides a new resource of information on Algerian medicinal plants used in the treatment and management of neurological and psychological diseases, which can be useful not only for the documentation and conservation of traditional knowledge, but also for conducting future phytochemical and pharmacological studies.

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“…Its essential oil, esteemed for its multifaceted properties, such as antibacterial, antioxidant, and anti-inflammatory effects, has found utility in various domains 3,19 , albeit recent concerns have arisen regarding its association with poisoning incidents. [20][21][22][23][24][25] Cedrus atlantica, family Pinaceae, is an endemic Moroccan species prized for its essential oil possessing antimicrobial, antifungal, and antioxidant properties. 26,27,[36][37][38][39][40][41][42][28][29][30][31][32][33][34][35] Widely utilized in construction due to its durability.…”

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confidence: 99%

Comparative Chemical and Biological Analysis of Wood and Tar Essential Oils from Cedrus atlantica and Juniperus oxycedrus in Morocco

2024

TJNPR

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Juniperus oxycedrus, a member of the Cupressaceae family, is indigenous to southern Europe and the Mediterranean basin, 4,[15][16][17][18] flourishing at altitudes between 1700 and 3000 meters in stony terrains. 3,19 Renowned for its ecological significance, Juniperus oxycedrus contributes to the regional economy through diverse applications, including firewood, natural ornamentation, and medicinal purposes. Its essential oil, esteemed for its multifaceted properties, such as antibacterial, antioxidant, and anti-inflammatory effects, has found utility in various domains 3,19 , albeit recent concerns have arisen regarding its association with poisoning incidents. [20][21][22][23][24][25] Cedrus atlantica, family Pinaceae, is an endemic Moroccan species prized for its essential oil possessing antimicrobial, antifungal, and antioxidant properties. 26,27,[36][37][38][39][40][41][42][28][29][30][31][32][33][34][35] Widely utilized in construction due to its durability. 30 Cedarwood also holds significance in Morocco's traditional therapeutic practices, 43 where cedar wood tar forms an integral part of the Magico-medical system, 44 utilized for treating skin conditions and eliminating parasites in animals. 32 These traditional forest species, deeply rooted in folk medicine, intrigue researchers for their potential applications. 43,45 This study presents a comparative analysis of the biological and antioxidant properties of wood tar essential oils extracted from Juniperus oxycedrus and Cedrus atlantica, using both lab-produced and artisanal samples. By exploring the composition and potential of these oils, the study aims to uncover similarities or distinctions between the two species, thereby contributing novel insights into their utility and applications in various fields.

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A rare case of cade oil poisoning complicated by acute pancreatitis and acute tubular necrosis

Cited by 4 publications

References 3 publications

Acute Systemic Toxicity Associated with Ingestion of Juniper Tar

Acute Systemic Toxicity Associated with Ingestion of Juniper Tar

Therapeutics to Treat Psychiatric and Neurological Disorders: A Promising Perspective from Algerian Traditional Medicine

Comparative Chemical and Biological Analysis of Wood and Tar Essential Oils from Cedrus atlantica and Juniperus oxycedrus in Morocco

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