A Rare Case of Benign Hamartoma and Malignant Primary Pulmonary Lymphoma Coexisting in a Patient Mimicking Invasive Pulmonary Mycosis:&#x0D;
a Case Report and Literature Review

Chen, Yi; Li, Li Q; Ge, Yan L; Xie, Bi X; Li, Wen Q; Jing, Qin; Liu, Yang; Lu, Yang; Sun, Yinghao; Min, Pei; Hou, Lin

doi:10.7754/clin.lab.2020.200646

Cited by 1 publication

(2 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…have been reported, [8][9][10] further confirming insufficient understanding between lymphoma and pneumonia. Some studies showed that discrimination between PPL presenting as consolidation and pneumonia may be beneficial in guiding early diagnosis, evaluation and initiation of therapy.…”

Section: Open Accessmentioning

confidence: 99%

“… 6 7 Kawel et al 2 tried to differentiate pulmonary aspergillosis and pulmonary lymphoma using CT. However, the sample size of previous studies was small, which may be due to the rarity of this condition and the lack of focus on the differential diagnosis of PPL presenting consolidation on CT. Additionally, numerous cases of lymphoma presenting as consolidation on CT mistaken for pneumonia have been reported, 8–10 further confirming insufficient understanding between lymphoma and pneumonia. Some studies showed that discrimination between PPL presenting as consolidation and pneumonia may be beneficial in guiding early diagnosis, evaluation and initiation of therapy.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Differential clinical and CT imaging features of pneumonic-type primary pulmonary lymphoma and pneumonia: a retrospective multicentre observational study

Li,

Wang,

Chang

et al. 2023

BMJ Open

View full text Add to dashboard Cite

IntroductionPneumonic-type primary pulmonary lymphoma (PPL) is often misdiagnosed as pneumonia in clinical practice. However, this disease requires different treatments, which calls for a correct diagnosis.Materials and methodsA total of 227 patients with pneumonic-type PPL (n=72) and pneumonia (n=155) from 7 institutions were retrospectively enrolled between January 2017 and January 2022. Clinical features (age, sex, cough, sputum, fever, haemoptysis, chest pain, smoking, weight loss and laboratory results (haemoglobin, white blood cell count, C reactive protein level and erythrocyte sedimentation rate)) and CT imaging characteristics (air bronchogram, bronchiectasis, halo sign, pleural traction, pleural effusion, lymphadenopathy, lesion maximum diameter and CT attenuation value) were analysed. Receiver operating characteristic curve analysis was performed for model construction based on independent predictors in identifying pneumonic-type PPL. In addition, we used a calibration curve and decision curve analysis to estimate the diagnostic efficiency of the model.ResultsThe patients with pneumonia showed a higher prevalence of sputum, fever, leucocytosis and elevation of C reactive protein level than those with pneumonic-type PPL (p=0.002, p<0.001, p=0.011 and p<0.001, respectively). Bronchiectasis, halo sign and higher CT attenuation value were more frequently present in pneumonic-type PPL than in pneumonia (all p<0.001). Pleural effusion was more commonly observed in patients with pneumonia than those with pneumonic-type PPL (p<0.001). Also, sputum, fever, elevation of C reactive protein level, halo sign, bronchiectasis, pleural effusion and CT attenuation value were the independent predictors of the presence of pneumonic-type PPL with an area under the curve value of 0.908 (95% CI, 0.863 to 0.942).ConclusionPneumonic-type PPL and pneumonia have different clinical and imaging features. These differential features could be beneficial in guiding early diagnosis and subsequent initiation of therapy.

show abstract

Section: Open Accessmentioning

confidence: 99%