A rare case of a pedunculated lipoma in the pharynx

Persaud, Raj; Kotnis, Rohit; Ong, Ching Ching; Bowdler, D. A.

doi:10.1136/emj.19.3.275

Cited by 17 publications

(13 citation statements)

References 3 publications

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“…Lipomas of the upper aerodigestive tract occur with continuous or intermittent symptoms over the course of a few months or years, which include dysphagia, hoarseness, feeling of discomfort in the throat like the feeling of a mass in the pharynx, and, in case of airway obstruction, stridor and dyspnea [ 8 ]. In severe but rare cases it is necessary to perform an emergency tracheostomy to prevent asphyxia and possible episodes of respiratory arrest [ 9 ].…”

Section: Discussionmentioning

confidence: 99%

Lipoma of Piriform Sinus: A Case Report and Review of the Literature

Acquaviva

Varakliotis

Badia

et al. 2016

Case Reports in Otolaryngology

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The lipomas of oropharynx, hypopharynx, and larynx are so rare that up to now approximately there have been 100 cases reported. The lipomas are slow-growing lesions that are capable of reaching considerable dimensions and are often detected at a late stage. The symptoms can vary both in dimension and in location, semiobstructing the aerodigestive tract or exerting compression on adjacent structure. In this case, the lesion, which originated from the piriform sinus, was removed endoscopically urgently due to obvious signs of tissue suffering caused by stretching of the pedicle as a result of displacement of the mass. The two aims of this case report are to expose an interesting and rare case study mainly for an Emergency Room Specialist and an ENT (Ear, Nose, and Throat) Specialist involved in solving the problem and to demonstrate that the choice of an endoscopic approach is useful in order to have an optimal visualization of the lesion and to perform a total eradication. The use of endoscopic devices also allows a rapid postoperative recovery, compared to external access and optimum locoregional control in the follow-up procedures to prevent possible relapses.

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Section: Discussionmentioning

confidence: 99%

Lipoma of Piriform Sinus: A Case Report and Review of the Literature

Acquaviva

Varakliotis

Badia

et al. 2016

Case Reports in Otolaryngology

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“…Thus, it was concluded that MDM-2 and CDK4 may be useful in the differential diagnosis between lipoma and ALT of the laryngopharynx. ALT of the laryngopharynx should be differentiated from other benign lipomatous tumors such as classical lipoma, spindle cell lipoma, and pleomorphic lipoma (Arista-Nasr et al, 1998;Jungehülsing et al, 2000;Cantarella et al, 2001;Persaud et al, 2002). However, the adipocytic cells in classical lipoma do not show hyperchromatic nuclei, a typical histological feature of ALT.…”

Section: Discussionmentioning

confidence: 99%

Clinicopathological features of atypical lipomatous tumors of the laryngopharynx

Shi

Wei

Wang

et al. 2010

J. Zhejiang Univ. Sci. B

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Atypical lipomatous tumor (ALT) of the laryngopharynx is rare. Here we report five cases to demonstrate their clinicopathological features. The patients were four males and one female, aged 41 to 69 years (median 53.6 years). All tumors (two in the hypopharynx and three in the larynx) presented as a slowly growing, painless mass. Symptoms included dysphagia (2/5), dysphonia (3/5), and the feeling of a foreign body in the throat (5/5). Tumors were well circumscribed or focally infiltrative, ranging from 2.0 to 5.0 cm (median, 3.4 cm) in size, and microscopically showed the typical features of lipoma-like ALT. Immunohistochemically, tumor cells were stained with S-100, vimentin, murine double minute 2 (MDM-2), and cyclin-dependent kinase 4 (CDK4). Two patients had local tumor recurrences at 6 and 14 months after initial surgery during follow-up. ALT of laryngopharynx is an indolent tumor. Immunohistochemical staining for MDM-2 and CDK4 is helpful in pathological diagnosis.

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“…These tumours are typically slow growing. However, they have the potential to cause airway obstruction depending on size and location and have been reported to cause stridor and death 2 3…”

Section: Descriptionmentioning

confidence: 99%