A rare case and unusual localization of a poorly differentiated giant synovial sarcoma of the ankle: Case report and literature review

A remarkable and aggressive aneurysmal bone cyst ravaging the femoral shaft, advancing to lung metastases: An extremely rare case

“…Giant cell tumors are made up of three types of cells: stromal cells, which are the only true tumor cells, mononuclear cells of the monocytic lineage (CD14+), and multinucleated giant cells of the osteoclastic lineage (CD33+ RANK+ CD14- CD163-). The stromal cells have an osteoblastic or pre-osteoblastic phenotype, with RUNX2, osterix, osteonectin, osteopontin, and SATB2 expression [ 3 , [7] , [8] , [9] , [10] ]. Some of them have recently been shown to have in vitro myofibroblastic differentiation potential.…”

A rare occurrence of a giant synovial sarcoma in the plantar region of the foot: A case report

“…While it typically manifests in adulthood, 30 % of reported cases involve adolescents and children. The tumor commonly presents as a slowly progressing mass [ 2 ], with a predilection for the lower and upper limbs, particularly the para-articular regions of large joints. Despite its name, synovial sarcoma does not seem to originate from the synovium; rather, it arises from multipotent stem cells that differentiate into epithelial and/or mesenchymal structures [ 3 ].…”