A rare association of Vagus Nerve Schwannoma and Pheochromocytoma: A case report

Harhar, Marouane; Harouachi, Abdelhakim; Bouhout, Tariq; Serji, Badr; Harroudi, Tijani El

doi:10.1016/j.amsu.2022.103475

Cited by 2 publications

(1 citation statement)

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“…Common histological features include the presence of fibrous capsule, Antoni A and Antoni B areas, cellular zones and Verocay bodies. Antoni A and Antoni B areas represent typical architectural histological features of schwannomas [ 35 , 36 ]. Type A tissue is highly cellular and demonstrates nuclear palisading and associated Verocay bodies, which reflects their prominent extracellular matrix and secretion of laminin.…”

Section: Discussionmentioning

confidence: 99%

Diagnostic and Therapeutic Strategy for Vagal Schwannoma: Case Series and Literature Review

et al. 2023

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Background and Objectives: Clinical management of vagal schwannoma is a real diagnostic and therapeutic challenge because the medical history and clinical examination are often non-specific and vagal nerve injury following surgical resection still represents an unsolved problem. The aim of this paper is to provide a case series along with a diagnostic and therapeutic algorithm for vagal schwannoma of the head and neck, combining our experience with clinical evidence available in the literature. Materials and Methods: We retrospectively analyzed a series of patients affected by vagal schwannoma who were treated between 2000 and 2020. In addition, a review of the literature on vagal schwannoma management was conducted. Based on the cases described and the literature review, we made a diagnostic and therapeutic algorithm for the management of vagal schwannoma. Results: We were able to identify 10 patients affected by vagal schwannoma and treated between 2000 and 2020. All patients presented with a painless, mobile, slow-growing lateral neck mass with onset varying from a few months to years. The preoperative diagnostic workup included ultrasound (US) in nine cases, computed tomography (CT) with contrast in six patients and magnetic resonance imaging (MRI) of the neck in seven cases. All patients included in this study were surgically treated. Conclusions: Vagal schwannoma management represents a true challenge for clinicians and surgery is currently the most effective therapeutic strategy. A multidisciplinary approach through the collaboration of otolaryngologist with other specialists is desirable to develop a tailored treatment plan for the patient.

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Section: Discussionmentioning

confidence: 99%

Diagnostic and Therapeutic Strategy for Vagal Schwannoma: Case Series and Literature Review

et al. 2023

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Cervical vagal nerve schwannoma induced arrhythmia: a rare case report and literature review

Chen

et al. 2022

BMC Neurol

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Background Schwannomas are benign tumors deriving from the sheath of cranial and peripheral nerves. The vagus nerve is comprised of a complex neuro-endocrine-immune network that maintains homeostasis, most tracts of it play a role in parasympathetic activity. We present an example of a rare cervical vagal schwannoma case accompanied by arrhythmia. Case presentation A 35-year-old female patient with a left cervical vagus schwannoma and ventricular arrhythmia underwent schwannoma resection in the operating room. The patient’s suppressed heart rate increased after tumor removal, and the cardiac rhythm returned to normal postoperatively. Pathological examination demonstrated the diagnosis of schwannoma. Conclusions This case explains the link between the vagus nerve and the cardiovascular system, proving that a damaged cervical vagus nerve can inhibit the heart rate and lead to arrhythmias, and eventually requiring surgical intervention.

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A rare association of Vagus Nerve Schwannoma and Pheochromocytoma: A case report

Cited by 2 publications

References 10 publications

Diagnostic and Therapeutic Strategy for Vagal Schwannoma: Case Series and Literature Review

Diagnostic and Therapeutic Strategy for Vagal Schwannoma: Case Series and Literature Review

Cervical vagal nerve schwannoma induced arrhythmia: a rare case report and literature review

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