A rapid, simple and reliable method for the screening of potential antiviral compoundsin vitro

Abstract

SummaryA rapid, simple method for the screening of large numbers of compounds for antiviral activity is described. The appropriate virus is grown in cell culture for one growth-cycle in the presence of test compound dilutions and viral growth is assessed by an indirect fluorescent antibody technique. Compound toxicity can be predetermined microscopically or by a quantitative method.