A rapid and sensitive method for the quantitation of montelukast in sheep plasma using liquid chromatography/tandem mass spectrometry

High-performance liquid chromatographic determination of montelukast sodium in human plasma: Application to bioequivalence study

“…No difference in pharmacokinetics was noted between dosing in the morning or in the evening [8,10]. Various analytical methods have been developed to determine montelukast in human plasma samples, such as LC-MS-MS [9,11], radiochromatographic [12], HPTLC [13], voltammetry [14], and chromatographic assays [15][16][17][18][19][20][21][22][23]. The use of columns switching [16][17], microtiter plate [19], and dual-column [20] has also been incorporated with the process of highperformance liquid chromatographic (HPLC) analysis.…”

“…Some methods do not use internal standards [17,20], whereas other methods use synthetic derivatives [15][16]19], quinine bisulfate [18], mefenamic acid [21], or ethoxyquin [23] as internal standards. Literature survey revealed that there is high variation in the limit of quantitation as reported by different authors (0.25 ng mL −1 [11]; 1-50 ng mL −1 [15][16][17][18][19][20][21][22][23]). All these methods utilize the 100-500 μL of plasma for sample processing.…”

“…This injection protocol was repeated after 1,3,8,11,15,22,25, and 30 days of storage of this solution between 4 and 8°C.…”

Development and validation of RP-HPLC method with ultraviolet detection for estimation of montelukast in rabbit plasma: Application to preclinical pharmacokinetics

“…1 A review of literature reveals that number of analytical and bioanalytical methods have been published for quantification of MKS. As long as bioanalysis of MKS is concerned there are great deal of methods ranging from voltammetry 2 to LC-MS/MS assays 3,4 have been reported. Amongst all reported bioanalysis assay methods, HPLC analysis with fluorescence detection 5,6,7 has been tried by many authors by various modifications either in instrumentation part or in sample preparation part.…”

Method development and validation for the simultaneous determination of fexofenadine hydrochloride and montelukast sodium using rp-hplc

“…Similarly for Montelukast sodium, UV spectrophotometry [19,20], spectrofluorometry [21], RP-HPLC [22,23], HPTLC [24,25], plasma HPLC [26,27,28,29], LC/MS [30,31], and stability indicating HPLC methods [32,33] have been reported.…”