“…The “day and night”, “24 h”, and “continuously” regimens were used in two [ 32 , 33 ], one [ 11 ], and two studies [ 34 , 35 ], respectively. In five studies, daily duration regimes changed consecutively, from “day and night” to “daytime” in two studies [ 36 , 37 ], from “day and night” to “8 h a day” in one [ 38 ], from “24 h” to “ daytime” in one [ 39 ], and from “24 h” to “while ambulatory” in one [ 40 ]. Other daily regimens used were “during walking hours” [ 41 ], “removed at night” [ 42 ], “throughout the day” [ 43 ], and “all day” [ 44 ].…”
Section: Resultsmentioning
confidence: 99%
“…Twenty-four RCTs were labelled as having a moderate risk of bias ( Figure 2 ) [ 11 , 14 , 25 , 26 , 27 , 30 , 31 , 32 , 33 , 34 , 35 , 36 , 38 , 40 , 41 , 42 , 43 , 45 , 47 , 48 , 50 , 52 , 58 , 61 ]. This was mainly due to no blinding of patients and/or researchers and a lack of descriptive information regarding study drop-out or withdrawals.…”
Background: There are no data on the daily regimen of compression therapy in patients with chronic venous disease. This systematic review aimed to establish the optimal daily duration of compression treatment. Methods: A systematic search of CENTRAL and MEDLINE was performed to identify RCTs, non-RCTs, reviews, systematic reviews, meta-analyses, and guidelines evaluating the use of compression regimens in the treatment of varicose veins. Results: Thirty-two RCTs, three non-RCTs, four observational studies, and two crossover trials reporting the duration and regimes of compression treatment fulfilled the inclusion criteria. The daily duration of compression was reported in patients after invasive treatment, for venous ulcer treatment, in patients with venous symptoms. The quality of the studies varied. We could not conduct a meta-analysis due to the heterogeneity of the research data and their quality. Twenty-three studies reported results of compression usage after invasive procedures. Eight studies reported daily duration regimens in patients with venous ulcers. Nine studies reported the impact of compression on venous symptoms and/or edema or limb volume change. One study was conducted to assess if compression improves QoL in venous patients. While there was a clear difference found in the daily duration depending on the clinical scenario, no data in support of exact regimens were found. Conclusions: There are no reliable data supporting exact daily regimens of compression treatment in various cohorts of CVD patients.
“…The “day and night”, “24 h”, and “continuously” regimens were used in two [ 32 , 33 ], one [ 11 ], and two studies [ 34 , 35 ], respectively. In five studies, daily duration regimes changed consecutively, from “day and night” to “daytime” in two studies [ 36 , 37 ], from “day and night” to “8 h a day” in one [ 38 ], from “24 h” to “ daytime” in one [ 39 ], and from “24 h” to “while ambulatory” in one [ 40 ]. Other daily regimens used were “during walking hours” [ 41 ], “removed at night” [ 42 ], “throughout the day” [ 43 ], and “all day” [ 44 ].…”
Section: Resultsmentioning
confidence: 99%
“…Twenty-four RCTs were labelled as having a moderate risk of bias ( Figure 2 ) [ 11 , 14 , 25 , 26 , 27 , 30 , 31 , 32 , 33 , 34 , 35 , 36 , 38 , 40 , 41 , 42 , 43 , 45 , 47 , 48 , 50 , 52 , 58 , 61 ]. This was mainly due to no blinding of patients and/or researchers and a lack of descriptive information regarding study drop-out or withdrawals.…”
Background: There are no data on the daily regimen of compression therapy in patients with chronic venous disease. This systematic review aimed to establish the optimal daily duration of compression treatment. Methods: A systematic search of CENTRAL and MEDLINE was performed to identify RCTs, non-RCTs, reviews, systematic reviews, meta-analyses, and guidelines evaluating the use of compression regimens in the treatment of varicose veins. Results: Thirty-two RCTs, three non-RCTs, four observational studies, and two crossover trials reporting the duration and regimes of compression treatment fulfilled the inclusion criteria. The daily duration of compression was reported in patients after invasive treatment, for venous ulcer treatment, in patients with venous symptoms. The quality of the studies varied. We could not conduct a meta-analysis due to the heterogeneity of the research data and their quality. Twenty-three studies reported results of compression usage after invasive procedures. Eight studies reported daily duration regimens in patients with venous ulcers. Nine studies reported the impact of compression on venous symptoms and/or edema or limb volume change. One study was conducted to assess if compression improves QoL in venous patients. While there was a clear difference found in the daily duration depending on the clinical scenario, no data in support of exact regimens were found. Conclusions: There are no reliable data supporting exact daily regimens of compression treatment in various cohorts of CVD patients.
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