“…This suggests that IDE volume, load and timing should be further investigated with regards to the blood pressure regulation during HD. Interestingly, a recent study compared the effect of IDE at the start of HD with IDE in the second half of HD (six sessions for each condition) on the incidence of IDH episodes (Rossum et al, 2023). The authors reported no difference between performing IDE in the first or second half of HD on the overall rate of IDH or on the incidence of symptomatic IDH, suggesting that IDE can be safely performed throughout HD treatment, if IDH is specifically addressed.…”