A Randomized Study Comparing High&amp;ndash;Energy TUMT to TURP: Quality&amp;ndash;of&amp;ndash;Life Results

Francisca, E.A.E.; d’Ancona, Frank; Hendriks, Jan C.M.; Kiemeney, Lambertus A.; Debruyne, F. M. J.; Rosette, Jean J.M.C.H. de la

doi:10.1159/000020357

Cited by 26 publications

(10 citation statements)

References 22 publications

(22 reference statements)

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“…At 12 months, all four trials reporting MadsenIversen symptom scores [166][167][168]213 reported higher (worse) scores following TUMT (Figure 3, comparison 01:02:03). Overall, the WMD was 1.97 (95% CI 1.27-2.66, p < 0.001).…”

Section: At 12 Monthsmentioning

confidence: 99%

“…Of the six eligible studies, three 165,166,213 (n = 290) provided information on IPSS/AUA scores (Appendix 8.1, Table 42). At 3 months IPSS was higher for TUMT than for TURP (Figure 3, comparison 01:01:01).…”

Section: Symptom Scores At 3 Monthsmentioning

confidence: 99%

“…Six RCTs, reported in 19 papers, 86,124,[165][166][167][168][169][207][208][209][210][211][212][213][214][215][216][217][218] were eligible for this comparison, in which a total of 549 participants were randomised. The number of participants randomised to TUMT or TURP ranged from 2 168 to 99.…”

Section: Characteristics Of Included Studiesmentioning

confidence: 99%

“…Again, there was marked statistical heterogeneity between the three studies. When a random-effects model was applied the direction of effect remained the same but the difference between the groups was no longer statistically significant (WMD 2.26, 95% CI -0.38 to 4.91).At 12 months, all four trials reporting MadsenIversen symptom scores [166][167][168]213 reported higher (worse) scores following TUMT (Figure 3, comparison 01:02:03). Overall, the WMD was 1.97 (95% CI 1.27-2.66, p < 0.001).…”

mentioning

confidence: 97%

“…Using a random-effects model did not change this pattern. The cause of heterogeneity is unclear but in the study by d'Ancona and colleagues 166 patients appear to have milder disease than in the other two studies.In total, four studies 166,168,210,213 (n = 306) provided information on the improvement of MadsenIversen scores after surgery (Appendix 8.1, Table 42). Meta-analysis of the four trials showed heterogeneity, with results tending to favour TURP, but the difference was not statistically significant ( Figure 3, comparison 01:02:01: WMD 0.63, 95% CI -0.08 to 1.33, p = 0.08).…”

mentioning

confidence: 99%

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Systematic review and economic modelling of effectiveness and cost utility of surgical treatments for men with benign prostatic enlargement

Lourenço

Armstrong²,

N’Dow³

et al. 2008

Health Technol Assess

116

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Systematic review and economic modelling of effectiveness and cost utility of surgical treatments for men with benign prostatic enlargement. Lourenco, T.; Armstrong, N.; N'Dow, J.; Nabi, G.; Deverill, M.; Pickard, R.; Vale, L.; MacLennan, G.; Fraser, C.; McClinton, S.; Wong, S.; Coutts, A.; Mowatt, G.; Grant, A. Published in: Health Technology Assessment Publication date: 2008 Document VersionPublisher's PDF, also known as Version of record Link to publication in Discovery Research Portal Citation for published version (APA):Lourenco, T., Armstrong, N., N'Dow, J., Nabi, G., Deverill, M., Pickard, R., ... Grant, A. (2008). Systematic review and economic modelling of effectiveness and cost utility of surgical treatments for men with benign prostatic enlargement. Health Technology Assessment, 12(35). General rightsCopyright and moral rights for the publications made accessible in Discovery Research Portal are retained by the authors and/or other copyright owners and it is a condition of accessing publications that users recognise and abide by the legal requirements associated with these rights.• Users may download and print one copy of any publication from Discovery Research Portal for the purpose of private study or research.• You may not further distribute the material or use it for any profit-making activity or commercial gain.• You may freely distribute the URL identifying the publication in the public portal. Take down policyIf you believe that this document breaches copyright please contact us providing details, and we will remove access to the work immediately and investigate your claim. Download date: 12. May. 2018 Health Technology Assessment 2008; Vol. 12: No. 35 Health Technology Assessment NIHR HTA Programme www.hta.ac.uk November 2008 Systematic review and economic modelling of effectiveness and cost utility of surgical treatments for men with benign prostatic enlargement How to obtain copies of this and other HTA Programme reports. An electronic version of this publication, in Adobe Acrobat format, is available for downloading free of charge for personal use from the HTA website (www.hta.ac.uk). A fully searchable CD-ROM is also available (see below).Printed copies of HTA monographs cost £20 each (post and packing free in the UK) to both public and private sector purchasers from our Despatch Agents.Non-UK purchasers will have to pay a small fee for post and packing. For European countries the cost is £2 per monograph and for the rest of the world £3 per monograph.You can order HTA monographs from our Despatch Agents:-fax (with credit card or official purchase order) -post (with credit card or official purchase order or cheque) -phone during office hours (credit card only).Additionally the HTA website allows you either to pay securely by credit card or to print out your order and then post or fax it. NHS libraries can subscribe free of charge. Public libraries can subscribe at a very reduced cost of £100 for each volume (normally comprising 30-40 titles). The commercial subscription rate is £3...

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Section: At 12 Monthsmentioning

confidence: 99%

Section: Symptom Scores At 3 Monthsmentioning

confidence: 99%

Section: Characteristics Of Included Studiesmentioning

confidence: 99%

mentioning

confidence: 97%

mentioning

confidence: 99%

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Systematic review and economic modelling of effectiveness and cost utility of surgical treatments for men with benign prostatic enlargement

Lourenço

Armstrong²,

N’Dow³

et al. 2008

Health Technol Assess

116

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Microwave thermotherapy for benign prostatic hyperplasia

Hoffman

Monga

Elliott

et al. 2007

Cochrane Database of Systematic Reviews

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Microwave thermotherapy techniques are effective alternatives to TURP and alpha-blockers for treating symptomatic BPH for men with no history of urinary retention or previous prostate procedures and prostate volumes between 30 to 100 mL. However, TURP provided greater symptom score and urinary flow improvements and reduced the need for subsequent BPH treatments compared to TUMT. Small sample sizes and differences in study design limit comparison between devices with different designs and energy levels. The effects of symptom duration, patient characteristics, or prostate volume on treatment response are unknown.

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Microwave thermotherapy for benign prostatic hyperplasia

Hoffman

Monga

Elliott

et al. 2012

Cochrane Database of Systematic Reviews

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Microwave thermotherapy techniques are effective alternatives to TURP and alpha-blockers for treating symptomatic BPH in men with no history of urinary retention or previous prostate procedures and prostate volumes between 30 to 100 mL. However, TURP provided greater symptom score and urinary flow improvements and reduced the need for subsequent BPH treatments compared to TUMT. Small sample sizes and differences in study design limit comparisons between devices with different designs and energy levels. The effects of symptom duration, patient characteristics, or prostate volume on treatment response are unknown.

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A Randomized Study Comparing High–Energy TUMT to TURP: Quality–of–Life Results

Cited by 26 publications

References 22 publications

Systematic review and economic modelling of effectiveness and cost utility of surgical treatments for men with benign prostatic enlargement

Systematic review and economic modelling of effectiveness and cost utility of surgical treatments for men with benign prostatic enlargement

Microwave thermotherapy for benign prostatic hyperplasia

Microwave thermotherapy for benign prostatic hyperplasia

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