A Randomized Intervention Trial of 24-wk Dairy Consumption on Waist Circumference, Blood Pressure, and Fasting Blood Sugar and Lipids in Japanese Men with Metabolic Syndrome

Tanaka, Shiro; Uenishi, Kazuhiro; Ishida, Hiromi; Takami, Yasuhiro; Hosoi, Takayuki; Kadowaki, Takashi; Orimo, Hajime; Ohashi, Yasuo

doi:10.3177/jnsv.60.305

Cited by 17 publications

(49 citation statements)

References 28 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Twenty-one of the thirty-one studies (68 %) instructed participants to consume low-fat, reduced-fat or no-fat dairy foods and one study supplied a low-fat Ca-fortified beverage containing 7 % non-specified milk ( 5 ) . Seven ( 2 , 8 , 37 , 39 , 43 – 45 ) of the remaining nine studies did not specify dairy fat content, one ( 40 ) instructed participants to choose either low- or full-fat dairy foods, and the other ( 6 ) specified daily energy from fat at 30 % in both the dairy supplemented and control groups.…”

Section: Resultsmentioning

confidence: 99%

Effect of increasing dietary calcium through supplements and dairy food on body weight and body composition: a meta-analysis of randomised controlled trials

et al. 2015

View full text Add to dashboard Cite

This meta-analysis of randomised controlled trials assessed the effect of Ca on body weight and body composition through supplementation or increasing dairy food intake. Forty-one studies met the inclusion criteria (including fifty-one trial arms; thirty-one with dairy foods (n 2091), twenty with Ca supplements (n 2711). Ca intake was approximately 900 mg/d higher in the supplement groups compared with control. In the dairy group, Ca intake was approximately 1300 mg/d. Ca supplementation did not significantly affect body weight (mean change (20·17, 95 % CI 2 0·70, 0·37) kg) or body fat (mean change (2 0·19, 95 % CI 20·51, 0·13) kg) compared to control. Similarly, increased dairy food intake did not affect body weight (20·06, 95 % CI 20·54, 0·43) kg or body fat change (2 0·36, 95 % CI 2 0·80, 0·09) kg compared to control. Sub-analyses revealed that dairy supplementation resulted in no change in body weight (nineteen studies, n 1010) (2 0·32, 95 % CI 20·93, 0·30 kg, P¼ 0·31), but a greater reduction in body fat (thirteen studies, n 564) (2 0·96, 95 % CI 21·46, 20·46 kg, P , 0·001) in the presence of energy restriction over a mean of 4 months compared to control. Increasing dietary Ca intake by 900 mg/d as supplements or increasing dairy intake to approximately 3 servings daily (approximately 1300 mg of Ca/d) is not an effective weight reduction strategy in adults. There is, however, an indication that approximately 3 servings of dairy may facilitate fat loss on weight reduction diets in the short term.

show abstract

Section: Resultsmentioning

confidence: 99%

Effect of increasing dietary calcium through supplements and dairy food on body weight and body composition: a meta-analysis of randomised controlled trials

et al. 2015

View full text Add to dashboard Cite

show abstract

“…However, these studies were conducted using Western populations, whereas we studied older community-dwelling Japanese subjects, who, in general, have lower milk product intake in their daily life than that of the Western population. For example, milk and milk product intake in Japan is reported to be ~60 kcal/day in middle-aged men [14] and ~150 kcal/day in adolescent females [47], which is similar to the values reported in the present study (Table 4) but is only one-fourth to one-third of those in US and European populations [48–50]. Therefore, the current consensus on the effects of milk protein supplementation based on the results from the Western populations [51] may not be simply applicable to Japanese populations.…”

Section: Discussionmentioning

confidence: 99%

“…On the other hand, nutritional supplementation studies suggest that daily milk product intake suppresses inflammatory responses and prevents LSDs [13, 14]. However, during the above interventions, because exercise intensity and energy expenditure were not monitored, it remains unknown how physical activity is involved in the effects of milk product intake.…”

Section: Introductionmentioning

confidence: 99%

Effects of milk product intake on thigh muscle strength and NFKB gene methylation during home-based interval walking training in older women: A randomized, controlled pilot study

et al. 2017

View full text Add to dashboard Cite

BackgroundMuscle atrophy with aging is closely associated with chronic systemic inflammation and lifestyle-related diseases. In the present study, we assessed whether post-exercise milk product intake during 5-month interval walking training (IWT) enhanced the increase in thigh muscle strength and ameliorated susceptibility to inflammation in older women.MethodsSubjects [n = 37, 66±5 (standard deviation) yrs] who had been performing IWT for >6 months participated in this study. They were randomly divided into the following 3 groups: IWT alone (CNT, n = 12), IWT + low-dose post-exercise milk product intake (LD, n = 12; 4 g protein and 3 g carbohydrate) or IWT + a 3-times higher dose of milk product intake than the LD group (HD, n = 13). They were instructed to repeat ≥5 sets of fast and slow walking for 3 min each at ≥70% and 40% peak aerobic capacity for walking, respectively, per day for ≥4 days/week.ResultsAfter IWT, thigh muscle strength increased in the HD group (8±2%) more than in the CNT group (-2±3%, P = 0.022), despite similar IWT achievements between the groups (P>0.15). Pyrosequencing analysis using whole blood showed that methylation of NFKB1 and NFKB2, master genes of inflammation, was enhanced in the HD group (29±7% and 44±11%, respectively) more than in the CNT group (-20±6% and -10±6%, respectively; P<0.001). Moreover, the genome-wide DNA methylation analysis showed that several inflammation-related genes were hyper-methylated in the HD group compared with that in the CNT group, suggesting greater pro-inflammatory cytokine gene suppression in the HD group.ConclusionHD milk product intake after exercise produced a greater percent increase in thigh muscle strength and NFKB1 and NFKB2 gene methylation during IWT in physically active older women.Trial registrationUMIN-CTR No. UMIN000024544 and No. UMIN000024912

show abstract

“…In addition, study protocols without results that were identified were excluded. Eighteen articles were excluded, and the remaining 10 articles [34][35][36][37][38][39][40][41][42][43] are summarized in Table 1.…”

Section: Current Review Of Rcts In Japanmentioning

confidence: 99%

“…The other studies found in our literature review focused on computer tailored advice 34,36) , telephone and mail support 37) , tailor-made lifestyle modification 40) , hot bathing 41) and dairy delivery 43) . Although all RCTs provided valuable findings, RCTs in this specific field in Japan were quite limited.…”

Section: Current Review Of Rcts In Japanmentioning

confidence: 99%

Current review of intervention studies on obesity and the role of physical activity in weight control

Nakata

Sasai

2015

JPFSM

View full text Add to dashboard Cite

Obesity is a major public health problem, both globally and in Japan. A nationwide approach targeting metabolic syndrome has routinely been conducted in Japan since April 2008; however, the obesity statistics have not improved. Promotion of physical activity is one anti-obesity strategy. Numerous observational studies have revealed inverse associations between obesity and physical activity; however, these results have not always been conducted as randomized controlled trials (RCTs) that can provide the highest level of evidence. Therefore, this review looks at RCTs in the field of obesity and physical activity worldwide. The Diabetes Prevention Program and the Look AHEAD study are representative RCTs in this field. A guideline for the management of overweight and obesity among U.S. adults has recently been updated using a systematic review of good-or fair-quality RCTs, but a comprehensive, systematic review of RCTs in Japan has not yet been undertaken. This review seeks to fill this gap. Overall, we only found 10 RCTs that met the three inclusion criteria ([1] intervention study on obesity, [2] overweight or obese Japanese participants, and [3] RCT) and did not meet the exclusion criterion (study protocol without results). Based on our review results, it is strongly suggested that more RCTs in this field be conducted in Japan.

show abstract

A Randomized Intervention Trial of 24-wk Dairy Consumption on Waist Circumference, Blood Pressure, and Fasting Blood Sugar and Lipids in Japanese Men with Metabolic Syndrome

Cited by 17 publications

References 28 publications

Effect of increasing dietary calcium through supplements and dairy food on body weight and body composition: a meta-analysis of randomised controlled trials

Effect of increasing dietary calcium through supplements and dairy food on body weight and body composition: a meta-analysis of randomised controlled trials

Effects of milk product intake on thigh muscle strength and NFKB gene methylation during home-based interval walking training in older women: A randomized, controlled pilot study

Current review of intervention studies on obesity and the role of physical activity in weight control

Contact Info

Product

Resources

About