A randomized, fellow eye, comparison of keratometry, aberrometry, tear film, axial length and the anterior chamber depth after eye rubbing in non-keratoconic eyes

Chervenkoff, Jordan V.; Hawkes, Elizabeth; Ortíz, Gabriela; Horney, Deborah; Nanavaty, Mayank A.

doi:10.1186/s40662-017-0084-8

Cited by 12 publications

(10 citation statements)

References 19 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Previous studies suggest that eye rubbing is associated with a spectrum of changes ranging from transient against-the-rule astigmatism to transient ectasialike corneal changes, which may develop over time into real keratoconus. [5][6][7][8][9][10] In their overview of managing chronic eye rubbing, McMonnies et al 23 discussed the possible factors associated with such a behavior regardless of a coexisting psychopathology. Such factors include learning disturbances, sleep prob-lems, and habit reactions, all of which may lead to increased stress in the affected person.…”

Section: Discussionmentioning

confidence: 99%

“…Repetitive mechanical irritation of the corneal surface has been shown to be a major risk factor for both disease occurrence and progression . Recurrent eye rubbing has been shown to cause transient ectasia-like corneal changes, which may transform into true keratoconus if mechanical irritation continues …”

Section: Introductionmentioning

confidence: 99%

“…2,5 Recurrent eye rubbing has been shown to cause transient ectasia-like corneal changes, which may transform into true keratoconus if mechanical irritation continues. [5][6][7][8][9][10] A common cause of repetitive eye rubbing in the pediatric population is atopia, which is associated with keratoconus. 5,11 Cognitive and psychiatric factors, which may also include repetitive eye rubbing, have been scarcely evaluated thus far in the context of keratoconus.…”

mentioning

confidence: 99%

See 2 more Smart Citations

Psychiatric Comorbidities Associated With Keratoconus

Safir,

Hecht,

Heller

et al. 2023

JAMA Ophthalmol

View full text Add to dashboard Cite

ImportanceEvaluating risk factors for keratoconus, often associated with recurrent eye rubbing, could generate hypotheses to be tested in future interventional trials.ObjectiveTo assess the risk for keratoconus associated with psychiatric comorbidities in adolescents and adults.Design, Setting, and ParticipantsThis population-based cross-sectional study included medical records of Israeli adolescents and adults in military service from January 2011 through December 2021.Main Outcomes and MeasuresThe prevalence of anxiety, obsessive compulsive disorder (OCD), autism, and attention-deficit/hyperactivity disorder (ADHD) was evaluated in individuals with and without keratoconus. The association between keratoconus and psychiatric comorbidities was tested using univariate and multivariant analyses.ResultsOverall, 940 763 adolescents and adults were included. Mean (SD) age was 17.56 (1.47) years, and 59.3% were male. Keratoconus was documented in 1533 individuals, with a prevalence of 0.16%. Patients with keratoconus were more likely to be diagnosed with ADHD compared with the general population (odds ratio [OR], 1.58; 95% CI, 1.38-1.81; P &lt; .001). After adjusting for age, sex, intellectual status, height, and weight, the results remained unchanged (hazard ratio, 1.46; 95% CI, 1.27-1.67; P &lt; .001). Stratification according to age showed an association between keratoconus and ADHD for males (OR, 1.62; 95% CI, 1.39-1.90; P &lt; .001) but not for females (OR, 1.29; 95% CI, 0.96-1.74; P = .09).Conclusions and RelevanceIn a large cohort of adolescents and adults, ADHD was associated with a diagnosis of keratoconus in male patients, even after adjusting for possible confounders. Although a causative effect could not be ascribed, these findings support further investigation into the potential value of education regarding eye rubbing in this population.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

mentioning

confidence: 99%

See 1 more Smart Citation

Psychiatric Comorbidities Associated With Keratoconus

Safir,

Hecht,

Heller

et al. 2023

JAMA Ophthalmol

View full text Add to dashboard Cite

show abstract

“…Lu et al concluded that tear film disruption makes the optical surface irregular and may cause aberrations or unpredictable keratometry measurements [37]. Additionally, Chervenkoff et al reported a significant change in central anterior K readings in healthy eyes following eye rubbing [38].…”

Section: Discussionmentioning

confidence: 99%

Stay-at-home myopia among school children during the COVID-19 pandemic

Sallam¹,

Mohammed²,

Karrar³

et al. 2022

Med Hypothesis Discov Innov Optom

View full text Add to dashboard Cite

Background: Uncorrected myopia represents a major cause of visual disability in children, especially in low-income and middle-income countries. However, there is still debate about the effect of e-learning and “stay-at-home” guidelines on the refractive status of school children, especially in the absence of long-term follow-up data. This study aimed to assess the impact of stay-at-home enforcement during the COVID-19 pandemic on myopia development or progression in students in the Suez Canal Area, Egypt. Methods: This longitudinal observational study included 1650 students. All students aged 8–15 years with visual complaints, who had attended routine annual vision checks since 2018, were enrolled and assessed annually for myopia development and progression until 2021. Cycloplegic and noncycloplegic refraction, axial length (AL), corneal curvature, and uncorrected and best-corrected distance visual acuity were measured. The participants were administered a questionnaire that focused mainly on collecting information on their visual habits. Results: Our study included 3,300 eyes of 1,650 school students with myopia during the 4-year study period from 2018 to 2021. The mean cycloplegic spherical equivalents (CSE) were - 1.02, - 1.52, - 2.00, and - 3.50 diopters (D) in 2018, 2019, 2020, and 2021, respectively. This myopic shift in CSE over time was significant (P < 0.001). The average keratometric reading (Avg K) increased significantly during the follow-up period (P < 0.001). The Avg K measurements were 42.32, 42.62, 43.02, and 44.19 D in 2018, 2019, 2020, and 2021, respectively. The changes in Avg K were significant (P < 0.001). The mean AL measurements were 22.53, 22.59, 22.69, and 22.71 mm in 2018, 2019, 2020, and 2021, respectively. Although statistically significant (P < 0.001), changes in AL were clinically insignificant throughout the study period. The mean durations spent on electronic devices at home were 2.12, 2.46, 3.10, and 6.00 hours in 2018, 2019, 2020, and 2021, respectively. The changes over time were significant (P < 0.001). Conclusions: During the COVID-19 pandemic, studying at home accelerated the degree of refraction toward myopia in school children in Egypt. Further studies are needed to assess the academic performance of students with progressive myopia.

show abstract

“…It is well known that eye rubbing induces changes in epithelial thickness, tear film, and keratometry. 29,30 However, until now, it has not been possible to prove that keratoconic topographic alterations are due to the effects of eye rubbing or to intrinsic disease.…”

Section: Discussionmentioning

confidence: 99%

Snake-like Chromatin Cell Protein as an Indicator of Chronic Eye Rubbing in Patients with Keratoconus and Allergic Conjunctivitis

Henríquez¹,

Canorio²,

Maldonado³

et al. 2018

International Journal of Keratoconus and Ectatic Corneal Diseases

View full text Add to dashboard Cite

Purpose:To evaluate the presence of snake-like chromatin (SLC) cell protein (related to eye rubbing) in patients with keratoconus or allergic conjunctivitis and in controls. Materials and methods:Prospective experimental study included 193 eyes of 193 patients between January 2015 and July 2016; 86 had a diagnosis of new keratoconus, 88 were controls, and 19 had a diagnosis of allergic conjunctivitis and underwent impression cytology (IC). Specimens were stained with a combination of periodic acid-Schiff (PAS) and Gill's modified papanicolaou stains to detect the presence of SLC cell protein and morphological characterization of dry eye and allergic conjunctivitis. A questionnaire regarding eye-rubbing habits was administered.Results: Of the patients, 56.97% (49/86 eyes) in the keratoconus group, 84.21% (16/19 eyes) in the allergy group, and 10.11% (9/89 eyes) in the control group reported rubbing their eyes. The SLC was detected in 24.41% (21/86), 73.68% (14/19), and 3.37% (3/89) of the keratoconus, allergy, and control groups respectively, who reported rubbing their eyes. In contrast, SLC was detected in 2.32% (2/86), 0% (0/19), and 1.12% (1/89) of the keratoconus, allergy, and control groups respectively, who reported not rubbing their eyes. Conclusion:The presence of SLC cells was higher in keratoconus, allergy, and control group patients who reported rubbing their eyes. Keratoconus is independent of eye-rubbing habits and the presence of SLC cells.

show abstract

A randomized, fellow eye, comparison of keratometry, aberrometry, tear film, axial length and the anterior chamber depth after eye rubbing in non-keratoconic eyes

Cited by 12 publications

References 19 publications

Psychiatric Comorbidities Associated With Keratoconus

Psychiatric Comorbidities Associated With Keratoconus

Stay-at-home myopia among school children during the COVID-19 pandemic

Snake-like Chromatin Cell Protein as an Indicator of Chronic Eye Rubbing in Patients with Keratoconus and Allergic Conjunctivitis

Contact Info

Product

Resources

About