A Randomized Double-Blind Study of Atomoxetine Versus Placebo for Attention-Deficit/Hyperactivity Disorder Symptoms in Children With Autism Spectrum Disorder

Assessment the Efficacy of Atomoxetine in Autism Spectrum Disorders: A Randomized, Double-Blind, Placebo-Controlled Trial

“…scores. Harfterkamp et al, (19) side effects were reported in 81.3% of patients who received Atomoxetine and 65.3% of the Placebo group. According to the present study side effects were reported in 55% of patients who received Atomoxetine and 15% of the Placebo group.…”

“…For example, Harfterkamp et al, (19) assessed 97 patients with ADHD and ASD, between the ages of 6-17 years, and were divided into 2 groups (Atomoxetine and placebo). The patients were evaluated through ADHD-RS, CGI-I, and conner's teacher rating scale-revisedshort form (CTRS-R:S).…”

“…The score of severity of illness are rated from 0 to 6 degrees too. The score of 1, are considered not at all ill; 2, borderline mentally ill; 3, mildly ill; 4, moderately ill; 5, markedly ill; 6, severely ill; 7, among the most extremely ill patients (19,20).…”

Autism spectrum disorder in adults: clinical features and the role of the psychiatrist

“…Two placebo-controlled trials have also found atomoxetine to be moderately effective and generally well toler ated in treating hyperactivity in this population (Arnold 2006;Hafterkamp 2012).…”

Autism spectrum disorder: advances in evidence-based practice

“…71,77 Early data suggest a similar role for α-2 adrenergic agonists, such as clonidine and guanfacine. 79 Repetitive behaviours Not all repetitive behaviours or restrictive interests in individuals with autism are interfering, and some behaviours can be shaped into functional skills.…”