A randomized controlled trial on the efficacy of synbiotic versus probiotic or prebiotic treatment to improve the quality of life in patients with ulcerative colitis
“…Bu durumun ise çalışma süresinin kısa olmasından kaynaklandığı vurgulanmıştır. 34 Ülseratif kolit hastalarının remisyon döne-minde kalmasında probiyotik kullanımı A düze-yinde; aktif dönemden remisyon dönemine girmesinin sağlanmasında ise B düzeyinde kanıtlar mevcuttur. 35 …”
Section: Probiyotikler Ve Prebiyotiklerunclassified
“…Bu durumun ise çalışma süresinin kısa olmasından kaynaklandığı vurgulanmıştır. 34 Ülseratif kolit hastalarının remisyon döne-minde kalmasında probiyotik kullanımı A düze-yinde; aktif dönemden remisyon dönemine girmesinin sağlanmasında ise B düzeyinde kanıtlar mevcuttur. 35 …”
Section: Probiyotikler Ve Prebiyotiklerunclassified
“…Previous studies in humans have suggested dietary fibers like alginate [85], chitosan [86], and inulin [87] lead to a reduction in potentially harmful microfloral metabolites. A range of small human interventions with various fermentable dietary fibers have shown significant, but small, clinical benefit in a number of intestinal diseases and disorders either on their own or in combination with probiotics [88][89][90].…”
“…[149] Following a systematic review of studies using VSL#3 TM , E.coli Nissle 1917 and Yakult TM , Mallon et al concluded that the addition of probiotics to conventional medical therapy had no effect in overall remission rate in mild to moderate UC. [150][151][152] Other randomized controlled trials have also shown conflicting results with some showing a higher rate of remission (with VSL#3 or a combination of a prebiotic and B.longum) [153][154][155] and others showing little or no benefit (with E.coli Nissle 1917). [156] There are no recommendations regarding the use of probiotics as maintenance therapy in UC.…”
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