A randomized controlled trial of Kundalini yoga in mild cognitive impairment

Eyre, Harris A.; Siddarth, Prabha; Acevedo, Bianca P.; Dyk, Kathleen Van; Paholpak, Pongsatorn; Ercoli, Linda M.; Cyr, Natalie St.; Yang, Hongyu; Khalsa, Dharma Singh; Lavretsky, Helen

doi:10.1017/s1041610216002155

Cited by 106 publications

(145 citation statements)

References 46 publications

Supporting

Mentioning

137

Contrasting

Unclassified

Order By: Relevance

“…A total of 32 randomized clinical trials with 3624 participants were included in the analysis. The age of the included participants ranged from 50 to 85 years.…”

Section: Resultsmentioning

confidence: 99%

“…Because mind‐body exercise is a nonpharmacologic therapy, nearly all of the studies failed to blind the participants and personnel. The outcome assessments were blinded in 20 studies (62.5%) . Thirty studies (93.75%) had a low risk of attrition bias because most studies reported the dropout rate or represented detailed explanations.…”

Section: Resultsmentioning

confidence: 99%

“…The outcome assessments were blinded in 20 studies (62.5%) . Thirty studies (93.75%) had a low risk of attrition bias because most studies reported the dropout rate or represented detailed explanations. Overall, 21 studies (65.6%) 16–22,24,25,27–29,33–35,37–40 were recognized as having a low risk of methodological quality, and the remaining studies were deemed to have a low methodological quality.…”

Section: Resultsmentioning

confidence: 99%

“…The treatments used for the intervention groups included tai chi, [14][15][16][17]25,26,28,29,31,33,[35][36][37][38][39][40]42,43 yoga, 13,[21][22][23][24]32,34,41 and dance. 12,[18][19][20]27,30 Different practices of mind-body exercises included varied schools that were12/24-form Yang-style tai chi, ballroom dance, Iyengar or Kundalini yoga, and so on (the detailed schools are shown in Supplementary Table S1).…”

Section: Characteristics Of the Included Studiesmentioning

confidence: 99%

“…Among the 32 RCTs, 24 studies (75%) 13,[16][17][18][19][20][21][22]24,25,[27][28][29][30][33][34][35][36][37][38][39][40]42,43 reported random sequence generation using appropriate methods such as a random number table, computer generation, or block or stratified randomization, and 15 studies (46.9%) 16,[19][20][21][22]24,25,[27][28][29]35,37,40,42,43 reported the use of allocation concealment methods. Because mindbody exercise is a nonpharmacologic therapy, nearly all of the studies failed to blind the participants and personnel.…”

Section: Quality Assessment Of Included Studiesmentioning

confidence: 99%

See 4 more Smart Citations

Effects of Mind‐Body Exercises on Cognitive Function in Older Adults: A Meta‐Analysis

Zheng

et al. 2018

J American Geriatrics Society

View full text Add to dashboard Cite

BACKGROUND/OBJECTIVES Mind‐body exercise has positive effects on cognitive performance, according to clinical observation and experts’ recommendations. However, its potential benefits for the cognitive function of aging adults are uncertain and still lack systematic estimations. Therefore, we conducted a systematic review and meta‐analysis to evaluate the overall efficacy and effectiveness of mind‐body exercises for cognitive performance in aging individuals with or without cognitive impairment. DESIGN A systematic review and meta‐analysis. SETTING AND PARTICIPANTS We searched related trials through June 2018 from four databases: Medline, Embase, PsycINFO (all via Ovid), and the Cochrane Library/Central Register of Controlled Trials. MEASUREMENTS Methodological quality was assessed using the Cochrane Risk of Bias Tool. A meta‐analysis of comparative effects was performed using Review Manager v.5.3 software, and publication bias was examined using Egger's test. RESULTS A total of 32 randomized controlled trials with 3624 participants were ultimately included in this meta‐analysis. The results revealed that mind‐body exercises as a whole had benefits in improving global cognition compared with that of the control group (mean difference [MD] = 0.92; 95% confidence interval [CI] = 0.33‐1.51; p = .002) and were more effective than control interventions in promoting cognitive flexibility (MD = −8.80; 95% CI = −15.22 to −2.38; p = .007), working memory (MD = 0.32; 95% CI = 0.01‐0.64; p = .05), verbal fluency (standardized mean difference [SMD] = 0.27; 95% CI = 0.09‐0.45; p = .003), and learning (SMD = 0.24; 95% CI = 0.10‐0.39; p = .001) on cognitively intact or impaired older adults. In dose‐subgroup analysis, only moderate exercise intensity (60‐120 min per week) significantly increased global cognition scores compared with those of the control group (MD = 1.15; 95% CI = 0.34‐1.97; p = .006). CONCLUSION Mind‐body exercises, especially tai chi and dance mind‐body exercise, are beneficial for improving global cognition, cognitive flexibility, working memory, verbal fluency, and learning in cognitively intact or impaired older adults. Moderate intensity is recommended as the optimal dose for older adults. J Am Geriatr Soc 67:749–758, 2019.

show abstract

“…A total of 32 randomized clinical trials with 3624 participants were included in the analysis. The age of the included participants ranged from 50 to 85 years.…”

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Characteristics Of the Included Studiesmentioning

confidence: 99%

Section: Quality Assessment Of Included Studiesmentioning

confidence: 99%

See 3 more Smart Citations

Effects of Mind‐Body Exercises on Cognitive Function in Older Adults: A Meta‐Analysis

Zheng

et al. 2018

J American Geriatrics Society

View full text Add to dashboard Cite

show abstract

Comparative Efficacy of Multicomponent Behavioral Interventions for Mild Cognitive Impairment

Laird

Lavretsky

2019

JAMA Netw Open

Self Cite

View full text Add to dashboard Cite

show abstract

Effects of mindfulness‐based interventions on neuropsychiatric symptoms and psychological well‐being on people with subjective cognitive decline and mild cognitive impairment: A meta‐analysis

Rose Sin Yi,

Jing Jing,

Hammoda

et al. 2023

Int J Geriat Psychiatry

View full text Add to dashboard Cite

ObjectivesNeuropsychiatric symptoms (NPS) are highly prevalent in individuals with subjective cognitive decline (SCD) and mild cognitive impairment (MCI), and are strongly linked to accelerated cognitive decline and dementia onset. While mindfulness‐based interventions have shown promise in improving psychological well‐being in clinical and community settings, their efficacy for individuals in these pre‐dementia stages remains unclear. This meta‐analysis examined the effects of mindfulness‐based interventions on NPS and psychological outcomes in these preclinical cohorts.MethodsEligible studies were retrieved from PubMed, EMBASE, JBI EPB, Web of Science, and Cochrane library. Two independent researchers conducted the literature search and data extraction. Cochrane Risk‐of‐Bias Assessment Tool was used to assess the methodological quality of included studies. Quality of evidence was evaluated using the GRADE approach. Intervention effects were estimated by Hedge's g and 95% confidence interval (CI).ResultsA total of 18 randomized controlled trials (including 974 participants from 21 studies) were included in the meta‐analysis. The results demonstrated statistically significant immediate post‐intervention effects of mindfulness‐based interventions on anxiety (g = −0.30, 95% CI −0.49 to −0.11), stress (g = −0.58, 95% CI −0.91 to −0.24), and quality of life (g = 0.50, 95% CI 0.12–0.87). However, no significant effects were found for depression, apathy, mindfulness, and stress‐related biomarkers. Follow‐up data analysis also did not reveal significant effects for depression and anxiety.ConclusionsThe findings of this meta‐analysis suggest that mindfulness‐based interventions may improve anxiety, stress, and quality of life in individuals with SCD and MCI. However, more rigorous randomized controlled trials with larger sample sizes and evaluation using physiological parameters are needed to establish more definitive conclusions. Future interventions could consider incorporating cognitive training and health education to address the specific needs of the pre‐dementia population.Registration NumberPROSPERO: CRD42022359906.

show abstract

A randomized controlled trial of Kundalini yoga in mild cognitive impairment

Cited by 106 publications

References 46 publications

Effects of Mind‐Body Exercises on Cognitive Function in Older Adults: A Meta‐Analysis

Effects of Mind‐Body Exercises on Cognitive Function in Older Adults: A Meta‐Analysis

Comparative Efficacy of Multicomponent Behavioral Interventions for Mild Cognitive Impairment

Effects of mindfulness‐based interventions on neuropsychiatric symptoms and psychological well‐being on people with subjective cognitive decline and mild cognitive impairment: A meta‐analysis

Contact Info

Product

Resources

About