“…From a neurophysiological perspective, it could potentially strengthen inhibitory control circuits and executive function, whose dysfunction is implicated in addictive disorders (Volkow & Li, 2004). Mindfulness-based therapies have been used previously in the treatment of depression (Segal, Williams, & Teasdale, 2002), prison recidivism (Coulter, 2002, HIV/AIDS (Robinson, Mathews, & Witek-Janusek, 2003;Williams et al, 2005), and alcohol and drug abuse (Alterman, Koppenhaven, Mulholland, Ladden, & Blaime, 2004;Avants, Beitel, & Margolin, 2005;Marlatt, 2002;Marlatt et al, 2004;Witkiewitz, Marlatt, & Walker, 2005).In this article, we focus on a manual-guided, cognitive-behavioral, spiritualityfocused, psychotherapy-spiritual self-schema (3-S) therapy-that is not solely mindfulness training, but rather has mindfulness training as one of its primary components. An eight-session version of 3-S therapy, developed for drug users whose HIV-serostatus is negative or unknown, has shown efficacy in a randomized clinical trial (Margolin, Beitel, Schuman-Olivier, & Avants, 2006): Specifically, the addition of 3-S therapy to standard addiction treatment decreased HIV risk behavior and increased spiritual practices and motivation for abstinence and HIV prevention.…”