A randomized controlled trial evaluating the effect of an internet-based cognitive-behavioral program on anxiety symptoms in a community-based sample of adolescents

O'Connor, Kathleen; Bagnell, Alexa; Rosychuk, Rhonda J.; Chen, Anqi A.; Lingley-Pottie, Patricia; Radomski, Anna; Öhinmaa, Arto; Joyce, Anthony S.; McGrath, Patrick J.; Newton, Amanda S

doi:10.1016/j.janxdis.2022.102637

Cited by 5 publications

(11 citation statements)

References 32 publications

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“…While most studies in the Internet-based interventions field have been conducted in adult samples, there is an increasing number of Internet-based psychosocial interventions for various mental health disorders and conditions in adolescence. Most commonly, Internet-based intervention trials target depression [10], anxiety [11], or chronic medical conditions [12].…”

Section: Introductionmentioning

confidence: 99%

Internet-based stress recovery intervention for adolescents: study protocol for a randomized controlled trial

Želvienė

Kairyte

Dumarkaitė

et al. 2023

Trials

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Background Research reveals a high prevalence of stressors in adolescence. Mental health in adolescence is highly related to life-stressors exposure and difficulties in adjusting to stressors. Therefore, interventions for recovery from stress are in high demand. The study aims to evaluate the efficacy of the Internet-based stress recovery intervention for adolescents. Methods A two-arm randomized controlled trial (RCT) on the efficacy of the FOREST-A—an Internet-based stress recovery intervention for adolescents—will be conducted. The FOREST-A is an adapted version of stress recovery intervention initially developed for healthcare workers. FOREST-A is a third-wave cognitive behavioral therapy and mindfulness-based Internet-delivered 4-week psychosocial intervention, which comprises six modules: Introduction, Relaxation, Psychological detachment, Mastery, Control, and Summary. The intervention will be evaluated using the two-arm RCT with intervention and care as usual (CAU) condition at pre-test, post-test, and 3-month follow-up. The measured outcomes will be stress recovery, adjustment disorder, generalized anxiety and depression symptoms, psychological well-being, and perceived positive social support. Discussion The study will contribute to the development of Internet interventions—easily and broadly accessible tools—for the enhancement of adolescents’ stress recovery skills. Based on the study’s findings, further development of the FOREST-A, including upscaling and implementation, is foreseen. Trial registration ClinicalTrials.gov NCT05688254. Registered on January 6, 2023.

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Section: Introductionmentioning

confidence: 99%

Internet-based stress recovery intervention for adolescents: study protocol for a randomized controlled trial

Želvienė

Kairyte

Dumarkaitė

et al. 2023

Trials

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“…All participants displayed emerging subclinical symptomatology. Youth COMPASS (Lappalainen et al, 2021(Lappalainen et al, , 2023, iSOMAguided (Hennemann et al, 2022a(Hennemann et al, , 2022b and BREATHE (6-module version) (O'Connor et al, 2022;Radomski et al, 2020). Table 4 provides a detailed description of included interventions.…”

Section: Participant Characteristicsmentioning

confidence: 99%

“…Intervention engagement period ranged from 20 days to 12 weeks (M = 7.34 weeks). Where reported, the average number of modules per intervention was 6.22 (range 3-12, n = 22 interventions), and the average number of modules intended to be completed per week of the intervention (Lappalainen et al, 2021(Lappalainen et al, , 2023, iSOMA-guided (Hennemann et al, 2022a(Hennemann et al, , 2022b and BREATHE (O'Connor et al, 2022;Radomski et al, 2020)], in no cases were the human support methods compared. Mental health professionals were the primary providers of guided intervention content (n = 12 interventions, 43%), followed by interventions delivered by clinicians and psychology students together (n = 6 interventions, 21%), and peers (n = 3, Harra & Vargas, 2023;Klimczak et al, 2023;Rodriguez et al, 2021).…”

Section: Intervention Characteristicsmentioning

confidence: 99%

“…Twenty-three studies assessed anxiety symptoms, including three studies that assessed social anxiety (Novella et al, 2022;Rice et al, 2020;Stapinski et al, 2021) and one assessing academic anxiety (Radomski et al, 2020) A number of studies reported that intervention groups observed significantly greater short-to long-term anxiety symptom reductions when compared to either an inactive (Küchler et al, 2023;O'Connor et al, 2022;Radomski et al, 2020;Radovic et al, 2021) or active control group (Küchler et al, 2023;Stapinski et al, 2021;Sun et al, 2022, p values ≤ 0.001-0.43). In contrast, no significant differences between intervention and active/inactive control on anxiety outcomes were reported for many interventions (Cook et al, 2019;Harra & Vargas, 2023;Hennemann et al, 2022b;Karyotaki et al, 2022;Klimczak et al, 2023;Lappalainen et al, 2023;Novella et al, 2022;Pescatello et al, 2021;Rodriguez et al, 2021), demonstrating substantial heterogeneity across anxiety results.…”

Section: Anxiety Symptomsmentioning

confidence: 99%

“…Three web-delivered studies assessed quality of life via the EQ-5D (Karyotaki et al, 2022), WHOQOL-BREF (Juniar et al, 2022), and YQOL-SF (O'Connor et al, 2022). Two of the included studies were two-arm RCTs (Karyotaki et al, 2022;O'Connor et al, 2022) and the remaining study (Juniar et al, 2022) Both RCTs found no significant differences when comparing an intervention group to an inactive control. This was observed immediately post intervention (p > 0.05, Karyotaki et al, 2022) and at 3 to 12-month follow-up (Karyotaki et al, 2022, p > 0.05;O'Connor et al, 2022, p = 0.23).…”

Section: Quality Of Lifementioning

confidence: 99%

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Outcomes of Best-Practice Guided Digital Mental Health Interventions for Youth and Young Adults with Emerging Symptoms: Part I. A Systematic Review of Socioemotional Outcomes and Recommendations

Opie,

Vuong,

Welsh

et al. 2024

Clin Child Fam Psychol Rev

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Youth-specific digital mental health interventions (DMHI) represent an emerging field of study, and aim to increase access, improve socioemotional outcomes, and, where required, support triage to targeted interventions. However, prior reviews have reported inconsistent findings on the clinical effectiveness of such interventions in young adults (12–25 years). Further, shortfalls remain for the impact of guided interventions based on the mode of delivery and the type of human support personnel (e.g., professional or peer) guiding the intervention. In response, this systematic review, co-designed with Australia’s leading mental health organization, aims to assess the effectiveness of guided digital programs in improving youth socioemotional outcomes. Included studies involve young people experiencing mental ill-health, receiving brief (i.e., 1–12 sessions), digitally delivered (at least partially) psychological interventions that were guided or partially guided, tested in a type of experimental study, with a socioemotional outcome. Specific socioemotional outcomes examined were depression, anxiety, stress, wellbeing, mindfulness, and quality of life. A systematic search of the contemporary published and grey literature identified 22,482 records with 32 relevant records published between 2018 and 2023. A narrative synthesis guided integration of findings. Results demonstrated strong evidence for the effectiveness of guided interventions on socioemotional outcomes (i.e., depression, anxiety, stress) yet these effects were short-lived. When factoring in the use of different control groups (i.e., active vs. inactive), inconsistent effects were observed for the socioemotional outcomes of depression, anxiety, and stress. The mode of delivery (i.e., asynchronous, synchronous, combined) and the type of human support personnel did not appear to impact socioemotional outcomes. Results indicate efficacious brief digital interventions for depression and anxiety include refresher/follow-up content, goal setting content, and relapse prevention content. In contrast, poor efficacy is associated with interventions that include homework tasks, self-monitoring, and log-keeping content.PROSPERO, ID CRD42023405812.

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The genetic architecture of youth anxiety: a study protocol

McAusland,

Burton,

Bagnell

et al. 2024

BMC Psychiatry

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Background Anxiety disorders are the most common psychiatric problems among Canadian youth and typically have an onset in childhood or adolescence. They are characterized by high rates of relapse and chronicity, often resulting in substantial impairment across the lifespan. Genetic factors play an important role in the vulnerability toward anxiety disorders. However, genetic contribution to anxiety in youth is not well understood and can change across developmental stages. Large-scale genetic studies of youth are needed with detailed assessments of symptoms of anxiety disorders and their major comorbidities to inform early intervention or preventative strategies and suggest novel targets for therapeutics and personalization of care. Methods The Genetic Architecture of Youth Anxiety (GAYA) study is a Pan-Canadian effort of clinical and genetic experts with specific recruitment sites in Calgary, Halifax, Hamilton, Toronto, and Vancouver. Youth aged 10–19 (n = 13,000) will be recruited from both clinical and community settings and will provide saliva samples, complete online questionnaires on demographics, symptoms of mental health concerns, and behavioural inhibition, and complete neurocognitive tasks. A subset of youth will be offered access to a self-managed Internet-based cognitive behavioral therapy resource. Analyses will focus on the identification of novel genetic risk loci for anxiety disorders in youth and assess how much of the genetic risk for anxiety disorders is unique or shared across the life span. Discussion Results will substantially inform early intervention or preventative strategies and suggest novel targets for therapeutics and personalization of care. Given that the GAYA study will be the biggest genomic study of anxiety disorders in youth in Canada, this project will further foster collaborations nationally and across the world.

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A randomized controlled trial evaluating the effect of an internet-based cognitive-behavioral program on anxiety symptoms in a community-based sample of adolescents

Cited by 5 publications

References 32 publications

Internet-based stress recovery intervention for adolescents: study protocol for a randomized controlled trial

Internet-based stress recovery intervention for adolescents: study protocol for a randomized controlled trial

Outcomes of Best-Practice Guided Digital Mental Health Interventions for Youth and Young Adults with Emerging Symptoms: Part I. A Systematic Review of Socioemotional Outcomes and Recommendations

The genetic architecture of youth anxiety: a study protocol

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