Abstract:Objective: Insulin resistance and hyperinsulinemia plays an important role in pathogenesis of polycystic ovary syndrome (PCOS). Metformin, Myoinositol and D-chiro-inositol acts as insulin sensitizers and exerts a beneficial effects in PCOS. The objective is to compare the effect of metformin monotherapy versus a combination of metformin with Myoinositol and D-chiro-inositol in PCOS.Design: This study is a randomized controlled trial conducted over a period of 6 months. All overweight and obese women with PCOS … Show more
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