A randomized comparison of sirolimus- vs. paclitaxel-eluting stents for treatment of bifurcation lesions by single stent and kissing balloon: Results of the SINGLE KISS trial

Potential Benefit of Final Kissing Balloon Inflation After Single Stenting for the Treatment of Bifurcation Lesions

“…Another study found a similar incidence of angiographic restenosis at the side branch and MACE between SES-and PES-implanted bifurcation lesions with FKI. 26 These data suggest that the side branch is prone to angiographic restenosis following main branch stenting but, even though FKI can reduce the incidence of side-branch restenosis, clear clinical benefit of FKI has not been fully elucidated.…”

Comparison of failure rates of crossing side branch with pressure vs. coronary guidewire: a meta‐analysis

“…Six studies involving 648 patients reported failure rates of SB crossing with a pressure guidewire [20][21][22][23][24][25] and 11 studies reported failure rates of SB crossing with a coronary guide wire in a total of 2601 patients ( Fig. 1) [10,11,[13][14][15][16][17][26][27][28][29]. Baseline characteristics with inclusion and exclusion criteria as delineated by each study are presented in Tables 1 and 2.…”

“…Most importantly, there was no difference in the prevalence of true bifurcation lesions in studies using FFR (57%) vs. studies using FKBI (62%, P = 0Á58). There were missing data for the other variables but overall, most studies included patients with relatively normal LVEF except for Nasu et al that included patients with LVEF >30% but the average LVEF in the study population was not reported (Table 2b) [16]. Prevalence of comorbidities was heterogeneous, likely due to different underlying clinical risk profiles of respective study cohorts.…”

“…All six studies that performed FFR in the SB of CBL specifically reported failure to access SB with pressure wire [20][21][22][23][24][25]. Out of the 11 studies included that performed FKBI in CBL, four studies specifically mentioned failure to pass coronary guide wire in SB after MV stenting [11,13,16,17] while three studies had a 100% success rate [14,28,29]. The remaining four studies reported overall success rates of being able to perform FKBI which indirectly provided failure rates which were then used for the analyses [10,15,26,27].…”

“…There were four studies that specifically mentioned coronary wire crossing failure in SB after MV stenting (n = 1306) [11,13,16,17]. We excluded the remaining seven studies that either reported success in all lesions [14,28,29] or in which overall success with FKBI was reported [10,15,26,27].…”