A randomized blinded comparison of omeprazole and ranitidine in the treatment of chronic esophageal stricture secondary to acid peptic esophagitis

The Benign Strictures of the Esophagus

“…On the contrary, Swarbrick et al (21) and Silvis et al (25) found no significant difference among re-dilatation rates in a year.…”

“…This type of radiation strictures may require repeating dilatations and keeping the lumen open by placing a nasogastric tube (25). For the relief of symptoms, at least three dilatations are necessary and the recurrence rate is high.…”

“…Moreover, antiplatelet and anti-coagulant drugs must be stopped 5 days before the process. Prophylactic antibiotics must be given to patients with a high risk of endocarditis (25).…”

Tratamento das estenoses esofágicas por dilatação endoscópica em crianças e adolescentes

“…[17][18][19][20] The inability of total healing of the coexistent esophagitis is a predictive factor for the poor response to endoscopic dilatation. 19 There is a high rate of recurrence of erosive or ulcerating peptic esophagitis after discontinuation of acid-suppressive treatment even with documented esophageal healing.…”

“…19 There is a high rate of recurrence of erosive or ulcerating peptic esophagitis after discontinuation of acid-suppressive treatment even with documented esophageal healing. [17][18][19][20][21] Nevertheless, it is common knowledge that fundoplication in the pediatric population has significant rates of failure, and that the child may have to remain under clinical and endoscopic treatment after the procedure. 18,22 The efficacy and safety of omeprazole, combined with endoscopic treatment, defined a new pattern for the treatment of children with complicated reflux esophagitis, which should be the treatment of choice, reserving surgical treatment for refractory cases.…”