“…Most current studies have used a simple electrolyte solution, but amniotic fluid contains many trophic factors and other components that may be beneficial to the fetus. To develop an optimal "amniotic fluid" for optimal fetal growth and development, Baumgarten et al [ 6 ] designed a model of continuous amniotic fluid exchange around a fetal rabbit. Monitoring of fetal development and timely adjustment of the nutrient concentration during the medical practice are of great significance, including checking blood glucose daily, calculating weight gain, or checking insulin-like growth factor (IGF)-1 and IGF binding protein, which can also be treated as an indicator of fetal growth in the management of nutrition.…”