Abstract:In response to threats, animals display quiescent behaviors such as freezing and tonic immobility. How neuromodulatory states like stress affect these behaviors is not well understood. Here we describe a Caenorhabditis elegans quiescent behavior, post-response quiescence (PRQ), which is modulated by the C. elegans response to cellular stressors. Following an aversive mechanical or blue light stimulus, worms respond first by briefly moving, and then become more quiescent for a period lasting tens of seconds. PR… Show more
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