A questionnaire for rating health-related quality of life

Janković, Slobodan M.; Bogavac-Stanojević, Nataša; Mikulić, Iva; Izetbegović, Sebija; Iličković, Ivana; Krajnović, Dušanka; Mehmedika, Enra Suljic; Gojak, Refet; Mehičević, Admir; Gazibera, Belma; Mahmutbegović, Nevena; Stojadinovic, M; Janković, Nikola; Miljković, Sanja K.; Popović, Slađana; Blidarević, Bojan; Mugosa, Snezana; Đorđević, Zorana

doi:10.2478/sjph-2021-0035

Cited by 3 publications

(3 citation statements)

References 19 publications

(27 reference statements)

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“…In a multicenter clinical trial on 187 patients with TRH spironolactone as add-on therapy was more efficient than central antihypertensive clonidine, but complete control of blood pressure after 3 months of treatment was achieved in only 21% of patients. [18,19] In another multicentric clinical trial where 285 patients with TRH were taking spironolactone as add-on therapy during 12 weeks, [20] spironolactone was more efficient than placebo, bisoprolol or doxazosin, but blood pressure control was achieved in no more than 58% of patients. It seems that for development of spironolactone full effect in TRH patients at least 6 months of treatment is necessary, probably because this is the time needed to titrate the dose properly; in our study mean daily dose of spironolactone was 28.6 ± 10.5 mm Hg at visit 1, and then increased to 30.5 ± 11.1 mm Hg at visit 6, when higher response rate was achieved.…”

Section: Discussionmentioning

confidence: 99%

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Results of the trycort: Cohort study of add-on antihypertensives for treatment of resistant hypertension

et al. 2023

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Although true treatment resistant hypertension is relatively rare (about 7.3% of all patients with hypertension), optimal control of blood pressure is not achieved in every other patient due to suboptimal treatment or nonadherence. The aim of this study was to compare effectiveness, safety and tolerability of various add-on treatment options in adult patients with treatment resistant hypertension The study was designed as multi-center, prospective observational cohort study, which compared effectiveness and safety of various add-on treatment options in adult patients with treatment resistant hypertension. Both office and home blood pressure measures were recorded at baseline and then every month for 6 visits. The study cohort was composed of 515 patients (268 females and 247 males), with average age of 64.7 ± 10.8 years. The patients were switched from initial add-on therapy to more effective ones at each study visit. The blood pressure measured both at office and home below 140/90 mm Hg was achieved in 80% of patients with add-on spironolactone, while 88% of patients taking this drug also achieved decrease of systolic blood pressure for more than 10 mm Hg from baseline, and diastolic blood pressure for more than 5 mm Hg from baseline. Effectiveness of centrally acting antihypertensives as add-on therapy was inferior, achieving the study endpoints in <70% of patients. Adverse drug reactions were reported in 9 patients (1.7%), none of them serious. Incidence rate of hyperkalemia with spironolactone was 0.44%, and gynecomastia was found in 1 patient (0.22%). In conclusion, the most effective and safe add-on therapy of resistant hypertension were spironolactone alone and combination of spironolactone and a centrally acting antihypertensive drug.

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Section: Discussionmentioning

confidence: 99%

“…[17] Information regarding occurrence of adverse events was captured throughout the study, and standard clinical laboratory measurements were documented at the study visits. Health-related quality of life was measured at each visit by previously validated [18,19] visual analogue scale with a span from 0 to 100.…”

Section: Methodsmentioning

confidence: 99%

Results of the trycort: Cohort study of add-on antihypertensives for treatment of resistant hypertension

et al. 2023

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“…Prior to the PCA, the Kaiser-Meyer-Olkin measure of Sampling Adequacy (KMO) and Bartlett's test of sphericity were conducted to assess the sample suitability for this method. Then the factors were extracted based on Eigenvalues (>1.0), scree-plot, and factor loading (>0.3) 19 . The construct validity of the questionnaire was explored by the correlation of its overall result with the patients' EQ-5D, ESSPRI, OHIP-14, and ERQ scores, using Spearman's rank correlation.…”

Section: Statistical Data Analysis Was Performed In the Spss Statisti...mentioning

confidence: 99%

Translation, transcultural adaptation, and validation of the Serbian version of the PSS-QoL questionnaire: A pilot research

et al. 2023

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Background/Aim. Assessment of health-related quality of life is fundamental for a better understanding the disease?s effect on different aspects of patients? daily functioning and treatment modalities efficacy. Primary Sj?gren's Syndrome Quality of Life Questionnaire (PSS-QoL) is the first disease-specific instrument for evaluating health-related quality of life in patients with primary Sj?gren syndrome. The aim of this study was to formally translate the PSS-QoL questionnaire from English to Serbian, assess its psychometric properties, and validate it for use in the Serbian population. Methods. The research was designed as a pilot study and included 30 participants. Internal consistency was determined by calculating Cronbach?s alpha coefficient. The construct validity of the questionnaire was estimated by the correlation of its overall result with the patients? EuroQoL-5D, EULAR SS Patients Reported Index, Oral Health Impact Profile-14, and Emotion Regulation Questionnaire scores. Results. There were 29 (96.7%) female participants and one (3.3%) male participant in the research. The average (? SD) score of PSS-QoL was 44.63 ? 12.901 at baseline and 41.70 ? 12.075 at follow-up. Cronbach?s alpha value of the Serbian version of PSS-QoL was 0.922. The test-retest intraclass correlation coefficient was 0.981 (95% CI: 0.436-0.996). Analysis revealed a statistically significant moderate to strong correlation between PSS-QoL scores and EuroQol-5D (rs = -0.696), EULAR SS Patients Reported Index (rs = 0.883), and Oral Health Impact Profile-14 scores (rs = 0.809). Conclusion. Serbian adaptation of the PSS-QoL instrument can be used to evaluate the health-related quality of life of patients with primary Sj?gren syndrome both in academic research and in clinical practice as a novel outcome measure.

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Translation, transcultural adaptation, and validation of the serbian version of the University of Washington Quality of Life questionnaire (UW-QoL) - a pilot study

Stanisic,

Dakovic,

Kozomara

et al. 2024

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Background/Aim. The University of Washington Quality of Life (UW-QoL) questionnaire is one of the most frequently applied instruments for the evaluation of the health-related quality of life of head and neck cancer patients worldwide. The aim of this study was to perform a formal translation of the original version into the Serbian language, assess its psychometric properties , and validate it for use in the Serbian-speaking population. Methods. The study was designed as pilot research and conducted between August and October 2023. The internal consistency of the questionnaire was established by calculating Cronbach?s alpha coefficient (CA). The intraclass correlation coefficient (ICC) was a measure of temporal stability. The construct validity of the instrument was assessed by correlating its total scores with Oral Health Impact Profile-14 (OHIP-14) and Emotion Regulation Questionnaire results. Results. A total of 30 patients (23 males and 7 females) with a mean age of 58.07 ? 13.59 years were enrolled in the research. Mean values of the physical function and social -emotional function subscales were 59.50 ? 12.68 and 55.39 ? 15.26 (the researchers interviewed the participants) and 58.78 ? 12.57 and 57.72 ? 14.91 (the patients completed the questionnaire by themselves). CA value of the Serbian version of the UW-QoL questionnaire was 0.816 (the questionnaire was filled out by the researchers) and 0.802 (the subjects completed it on their own). ICC was 0.797. There was a statistically significant strong correlation between the UW-QoL questionnaire and OHIP-14 total scores. The obtained results showed a weak, nonsignificant correlation between the UW-QoL questionnaire and the Emotion Regulation Questionnaire. Conclusion. Our pilot research showed that the Serbian version of the UW-QoL questionnaire appears as psychometrically valid and reliable as the original English version.

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A questionnaire for rating health-related quality of life

Cited by 3 publications

References 19 publications

Results of the trycort: Cohort study of add-on antihypertensives for treatment of resistant hypertension

Results of the trycort: Cohort study of add-on antihypertensives for treatment of resistant hypertension

Translation, transcultural adaptation, and validation of the Serbian version of the PSS-QoL questionnaire: A pilot research

Translation, transcultural adaptation, and validation of the serbian version of the University of Washington Quality of Life questionnaire (UW-QoL) - a pilot study

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