A quantum field theoretical approach to the collective behaviour of biological systems

Giudice, E. Del; Doglia, Silvia Maria; Milani, M.; Vitiello, Giuseppe

doi:10.1016/0550-3213(85)90267-6

Cited by 149 publications

(139 citation statements)

References 33 publications

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“…As Schrödinger observed for living matter in general (and his remarks apply equally well to the case of PCR processes), the attempt to explain the high efficiency in terms of ordering generated by "statistical mechanisms" * would be "the classical physicist's expectation that far from being trivial, is wrong" * , and "it needs * [18] (p. 47) * [18] (p. 19) no poetical imagination but only clear and sober scientific reflection to recognize that we are here obviously faced with events whose regular and lawful unfolding is guided by a mechanism entirely different from the probability mechanism of physics" * . We propose in this paper and in [5,6] that a third party intervenes in the DNA-enzyme interaction processes, which is organized (coherent) water, and we show how this fits well with the general gauge theory paradigm of quantum fields [15,16] (see also [7][8][9][10][11]). …”

Section: The Taq-dna Interaction and Open Questionsmentioning

confidence: 78%

“…The present article offers an explanation by using the formalism of the gauge theory paradigm of quantum fields along the research lines developed in Refs. [1,[5][6][7][8][9][10][11].…”

Section: Introductionmentioning

confidence: 99%

“…Eq. (9) means that any change in time of the difference between the phases of the amplitudes a 1 (t) and a 0 (t) is compensated by the change of phase of the em field. The coherence between the matter field and the em radiative dipole field guarantees the gauge invariance of the theory.…”

Section: Dna and Taq Coupling To The Water Dipole Fieldmentioning

confidence: 99%

See 2 more Smart Citations

Water Bridging Dynamics of Polymerase Chain Reaction in the Gauge Theory Paradigm of Quantum Fields

Montagnier¹,

Aïssa²,

Capolupo³

et al. 2017

Preprint

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Abstract:We discuss the role of water bridging the DNA-enzyme interaction by resorting to recent results showing that London dispersion forces between delocalized electrons of base pairs of DNA are responsible for the formation of dipole modes that can be recognized by Taq polymerase. We describe the dynamical origin of the high efficiency and precise targeting of Taq activity in PCR. The spatiotemporal distribution of interaction couplings, frequencies, amplitudes, and phase modulations comprise a pattern of fields instantiating the electromagnetic image of DNA in its water environment, which is what the polymerase enzyme actually recognizes at long range. The experimental realization of PCR amplification, achieved through replacement of the DNA template by the treatment of pure water with electromagnetic signals recorded from viral and bacterial DNA solutions, is found consistent with the gauge theory paradigm of quantum fields.

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Section: The Taq-dna Interaction and Open Questionsmentioning

confidence: 78%

“…The present article offers an explanation by using the formalism of the gauge theory paradigm of quantum fields along the research lines developed in Refs. [1,[5][6][7][8][9][10][11].…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Water Bridging Dynamics of Polymerase Chain Reaction in the Gauge Theory Paradigm of Quantum Fields

Montagnier¹,

Aïssa²,

Capolupo³

et al. 2017

Preprint

Self Cite

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show abstract

“…The external informational input acts as the trigger of the symmetry breakdown out of which the NG bosons and their condensation are generated. The symmetry which gets broken is the rotational symmetry of the electrical dipoles of the water molecules (Jibu and Yasue, 1995) and the NG modes are the vibrational dipole wave quanta (DWQ) (Del Giudice, et al 1985;1986;. The recall of the recorded information occurs under the input of a stimulus "similar" to the one responsible for the memory recording.…”

Section: Partmentioning

confidence: 99%

Nonlinear brain dynamics as macroscopic manifestation of underlying many-body field dynamics

Freeman

Vitiello

2006

Physics of Life Reviews

221

263

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Neural activity patterns related to behavior occur at many scales in time and space from the atomic and molecular to the whole brain. Patterns form through interactions in both directions, so that the impact of transmitter molecule release can be analyzed upwardly through synapses, dendrites, neurons, populations and brain systems to behavior, and control of that release can be described step-wise through top-down transformations. Here we explore the feasibility of interpreting neurophysiological data in the context of many-body physics by using tools that physicists have devised to analyze comparable hierarchies in other fields of science. We focus on a mesoscopic level that offers a multi-step pathway between the microscopic functions of neurons and the macroscopic functions of brain systems revealed by hemodynamic imaging. We use electroencephalographic (EEG) records collected from high-density electrode arrays fixed on the epidural surfaces of primary sensory and limbic areas in rabbits and cats trained to discriminate conditioned stimuli (CS) in the various modalities. High temporal resolution of EEG signals with the Hilbert transform gives evidence for diverse intermittent spatial patterns of amplitude (AM) and phase modulations (PM) of carrier waves that repeatedly re-synchronize in the beta and gamma ranges at near zero time lags over long distances. The dominant mechanism for neural interactions by axodendritic synaptic transmission should impose distance-dependent delays on the EEG oscillations owing to finite propagation velocities. It does not. EEGs instead show evidence for anomalous dispersion: the existence in neural populations of a low velocity range of information and energy transfers, and a high velocity range of the spread of phase transitions. This distinction labels the phenomenon but does not explain it. In this report we explore the analysis of these phenomena using concepts of energy dissipation, the maintenance by cortex of multiple ground states corresponding to AM patterns, and the exclusive selection by spontaneous breakdown of symmetry (SBS) of single states in sequences.

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“…The immediate consequence of SBS in material substrates is the condensation of quanta, called the Nambu-Goldstone boson particles, or waves or modes, in the least energy state of the system (the system ground state or vacuum). The symmetry which is considered is the electrical dipole rotational symmetry (Del Giudice, Doglia, et al, 1985;1986;Del Giudice, Preparata, et al, 1988;Jibu and Yasue, 1992;1995). As we discuss in what follows, we believe we can follow this same path, since the water matrix and any of the biomolecules entering the brain cellular components are endowed with a characteristic electric dipole moment.…”

mentioning

confidence: 99%

Nonlinear Brain Dynamics and Many-Body Field Dynamics

Freeman¹,

Vitiello²

2005

Electromagnetic Biology and Medicine

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We report measurements of the brain activity of subjects engaged in behavioral exchanges with their environments. We observe brain states which are characterized by coordinated oscillation of populations of neurons that are changing rapidly with the evolution of the meaningful relationship between the subject and its environment, established and maintained by active perception. Sequential spatial patterns of neural activity with high information content found in sensory cortices of trained animals between onsets of conditioned stimuli and conditioned responses resemble cinematographic frames. They are not readily amenable to description either with classical integrodifferential equations or with the matrix algebras of neural networks. Their modeling is provided by field theory from condensed matter physics.

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A quantum field theoretical approach to the collective behaviour of biological systems

Cited by 149 publications

References 33 publications

Water Bridging Dynamics of Polymerase Chain Reaction in the Gauge Theory Paradigm of Quantum Fields

Water Bridging Dynamics of Polymerase Chain Reaction in the Gauge Theory Paradigm of Quantum Fields

Nonlinear brain dynamics as macroscopic manifestation of underlying many-body field dynamics

Nonlinear Brain Dynamics and Many-Body Field Dynamics

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